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SOCAIL MEDIA
AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector system
(retina-validated AAV expression and packaging plasmid system)
AAV protocol Download
AAV User Manual Download
Capsid mutant-AAV serotype 2 variant(AAV2-(Y444F,Y730F,Y500F,Y272F,Y704F,Y252F)) system-Introduction
GeneMedi's AAV2 variant (Y444F, Y730F, Y500F, Y27variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) helper-free packaging plasmids system) is including AAV2 variant (Y444F,Y730F,Y500F,Y272F,Y704F,Y252F) Rep-Cap plamid (AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) -RC plasmid), AAV helper plasmid and AAV expression vectors (overexpression or shRNA).
You can choose your suiltable AAV expression vector plasmids from GeneMedi's AAV expression vector core. The AAV expression vector plasmids were constructed with differernt expression cassettes,containing kinds of verified protomters and reporters including GFP, zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.
AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) Rep-Cap plamid supplies the AAV2 Rep(replication) proteins and the AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) capsid-engineered protein.
The tissue tropism of AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector has been validated in retina (retinal ganglion cells) by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
| Product Name | Organization Type | Price(In USD) | Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector system Cat.No.:P-PK05 1. AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Academic | 3216 | ||
| AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector system Cat.No.:P-PK05 1. AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Industry R&D (excluding CRO&CDMO&CXO) | Inquiry | ||
| AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector system Cat.No.:P-PK05 1. AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) Rep-Cap plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug Expression vector refers only to B85, if you need other expression vector, please click →AAV Expression Vector list |
CRO&CDMO& CXO&CMC& Manufacturing company |
Inquiry | ||
| Shipping Cost: | 169.00 | |||
| Total: | ||||
AAV2 capsid variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) tissue tropism and gene transduction
(serotype-specific AAV infection)
The tissue tropism of AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F) vector has been validated in retina (retinal ganglion cells) by both intravitreal injection and sub-retinal injection with potential applications in retina gene therapy.
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Virus and titer: AAV2 variant (Y444F) vector system, 1×1012 vg/ml Animal: mouse, C57, 2 months Infection site: retina Gene delivery method: subretinal cavity injection, 3μl Determine assay: 3 weeks post infection, wholemount, immunofluorescence microscopy
Other AAV vector system
