human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha(IL27RA) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


Target products collectionGo to IL27R/IL27RA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha (IL27RA) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene. In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.


Order information


* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry

Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-IO077-Ag-1interleukin 27 receptor, alpha (IL27RA) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-IO077-Ab-1Anti-IL27RA monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-IO077-Ab-2Anti-IL27RA monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IO077-Ag-1interleukin 27 receptor, alpha (IL27RA)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IO077-Ab-1Anti-IL27RA monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IO077-Ab-2Anti-IL27RA monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IO077-Ag-1interleukin 27 receptor, alpha (IL27RA)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IO077-Ab-1Anti-IL27RA monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IO077-Ab-2Anti-IL27RA monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IO077-Ag-1interleukin 27 receptor, alpha (IL27RA)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IO077-Ab-1Anti-IL27RA monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IO077-Ab-2Anti-IL27RA monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIL27RA
Full nameinterleukin 27 receptor, alpha
Gene ID9466
Gene NameIL27RA
Gene AliasCRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-IO077-Ag-1, GM-Tg-rg-IO077-Ag-1, GM-Tg-mg-IO077-Ag-1, GM-Tg-cynog-IO077-Ag-1
Products Nameinterleukin 27 receptor, alpha (IL27RA) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha (IL27RA) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-IO077-Ab-1, GM-Tg-hg-IO077-Ab-2,
GM-Tg-rg-IO077-Ab-1, GM-Tg-rg-IO077-Ab-2,
GM-Tg-mg-IO077-Ab-1, GM-Tg-mg-IO077-Ab-2,
GM-Tg-cynog-IO077-Ab-1, GM-Tg-cynog-IO077-Ab-2
Products NameAnti-IL27R/IL27RA monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL27R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.