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human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor-like 2(CCRL2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to CCRL2/CCRL2 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor-like 2 (CCRL2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
C-C chemokine receptor-like 2 is a protein that in humans is encoded by the CCRL2 gene. Recently it was found that CCRL2 also acts as a receptor for the chemokine chemerin.
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-MP0191-Ag-1 | chemokine (C-C motif) receptor-like 2 (CCRL2) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP0191-Ab-1 | Anti-CCRL2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP0191-Ab-2 | Anti-CCRL2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0191-Ag-1 | chemokine (C-C motif) receptor-like 2 (CCRL2) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0191-Ab-1 | Anti-CCRL2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0191-Ab-2 | Anti-CCRL2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0191-Ag-1 | chemokine (C-C motif) receptor-like 2 (CCRL2) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0191-Ab-1 | Anti-CCRL2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0191-Ab-2 | Anti-CCRL2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0191-Ag-1 | chemokine (C-C motif) receptor-like 2 (CCRL2) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0191-Ab-1 | Anti-CCRL2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0191-Ab-2 | Anti-CCRL2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | CCRL2 |
| Full name | chemokine (C-C motif) receptor-like 2 |
| Gene ID | 9034 |
| Gene Name | CCRL2 |
| Gene Alias | ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-MP0191-Ag-1, GM-Tg-rg-MP0191-Ag-1, GM-Tg-mg-MP0191-Ag-1, GM-Tg-cynog-MP0191-Ag-1 |
| Products Name | chemokine (C-C motif) receptor-like 2 (CCRL2) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor-like 2 (CCRL2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-MP0191-Ab-1, GM-Tg-hg-MP0191-Ab-2, GM-Tg-rg-MP0191-Ab-1, GM-Tg-rg-MP0191-Ab-2, GM-Tg-mg-MP0191-Ab-1, GM-Tg-mg-MP0191-Ab-2, GM-Tg-cynog-MP0191-Ab-1, GM-Tg-cynog-MP0191-Ab-2 |
| Products Name | Anti-CCRL2 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCRL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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