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human, Cynomolgus/ Rhesus macaque, rat, mouse leucine-rich repeats and immunoglobulin-like domains 2(LRIG2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to LRIG2/LRIG2 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
LRIG2 (Leucine Rich Repeats And Immunoglobulin Like Domains 2) is a Protein Coding gene. Diseases associated with LRIG2 include Urofacial Syndrome 2 and Urofacial Syndrome 1. An important paralog of this gene is LRIG3.
This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-MP0750-Ag-1 | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP0750-Ab-1 | Anti-LRIG2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP0750-Ab-2 | Anti-LRIG2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0750-Ag-1 | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0750-Ab-1 | Anti-LRIG2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP0750-Ab-2 | Anti-LRIG2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0750-Ag-1 | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0750-Ab-1 | Anti-LRIG2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP0750-Ab-2 | Anti-LRIG2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0750-Ag-1 | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0750-Ab-1 | Anti-LRIG2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP0750-Ab-2 | Anti-LRIG2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | LRIG2 |
| Full name | leucine-rich repeats and immunoglobulin-like domains 2 |
| Gene ID | 9860 |
| Gene Name | LRIG2 |
| Gene Alias | LIG-2, LIG2, UFS2 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-MP0750-Ag-1, GM-Tg-rg-MP0750-Ag-1, GM-Tg-mg-MP0750-Ag-1, GM-Tg-cynog-MP0750-Ag-1 |
| Products Name | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-MP0750-Ab-1, GM-Tg-hg-MP0750-Ab-2, GM-Tg-rg-MP0750-Ab-1, GM-Tg-rg-MP0750-Ab-2, GM-Tg-mg-MP0750-Ab-1, GM-Tg-mg-MP0750-Ab-2, GM-Tg-cynog-MP0750-Ab-1, GM-Tg-cynog-MP0750-Ab-2 |
| Products Name | Anti-LRIG2 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-LRIG2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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