human, Cynomolgus/ Rhesus macaque, rat, mouse Transmembrane protein with EGF-like and two follistatin-like domains 2(TMEFF2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants.
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Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
GM-Tg-hg-MP1810-Ag-1 | Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-MP1810-Ab-1 | Anti-TMEFF2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-MP1810-Ab-2 | Anti-TMEFF2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-MP1810-Ag-1 | Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-MP1810-Ab-1 | Anti-TMEFF2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-MP1810-Ab-2 | Anti-TMEFF2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-MP1810-Ag-1 | Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-MP1810-Ab-1 | Anti-TMEFF2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-MP1810-Ab-2 | Anti-TMEFF2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-MP1810-Ag-1 | Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-MP1810-Ab-1 | Anti-TMEFF2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-MP1810-Ab-2 | Anti-TMEFF2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Target Information
Target Name | TMEFF2 |
Full name | Transmembrane protein with EGF-like and two follistatin-like domains 2 |
Gene ID | 23671 |
Gene Name | TMEFF2 |
Gene Alias | CT120.2, HPP1, TENB2, TPEF, TR, TR-2 |
Protein Sub-location | Transmembrane Protein |
Antigen Information
Cat No. | GM-Tg-hg-MP1810-Ag-1, GM-Tg-rg-MP1810-Ag-1, GM-Tg-mg-MP1810-Ag-1, GM-Tg-cynog-MP1810-Ag-1 |
Products Name | Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) protein |
Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
Tag | His |
Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse Transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
Catalog No. | GM-Tg-hg-MP1810-Ab-1, GM-Tg-hg-MP1810-Ab-2, GM-Tg-rg-MP1810-Ab-1, GM-Tg-rg-MP1810-Ab-2, GM-Tg-mg-MP1810-Ab-1, GM-Tg-mg-MP1810-Ab-2, GM-Tg-cynog-MP1810-Ab-1, GM-Tg-cynog-MP1810-Ab-2 |
Products Name | Anti-TMEFF2 monoclonal antibody |
Format | mab |
Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-TMEFF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |