human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain(TNFRSF10C) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Decoy receptor 1 (DCR1), also known as TRAIL receptor 3 (TRAILR3) and tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), is a human cell surface receptor of the TNF-receptor superfamily. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity		SizePrice
GM-Tg-hg-MP1854-Ag-1tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP1854-Ab-1Anti-TNFRSF10C monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP1854-Ab-2Anti-TNFRSF10C monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1854-Ag-1tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1854-Ab-1Anti-TNFRSF10C monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1854-Ab-2Anti-TNFRSF10C monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1854-Ag-1tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1854-Ab-1Anti-TNFRSF10C monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1854-Ab-2Anti-TNFRSF10C monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1854-Ag-1tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C)Cynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1854-Ab-1Anti-TNFRSF10C monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1854-Ab-2Anti-TNFRSF10C monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameTNFRSF10C
Full nametumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Gene ID8794
Gene NameTNFRSF10C
Gene AliasCD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-MP1854-Ag-1, GM-Tg-rg-MP1854-Ag-1, GM-Tg-mg-MP1854-Ag-1, GM-Tg-cynog-MP1854-Ag-1
Products Nametumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain (TNFRSF10C) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-MP1854-Ab-1, GM-Tg-hg-MP1854-Ab-2,
GM-Tg-rg-MP1854-Ab-1, GM-Tg-rg-MP1854-Ab-2,
GM-Tg-mg-MP1854-Ab-1, GM-Tg-mg-MP1854-Ab-2,
GM-Tg-cynog-MP1854-Ab-1, GM-Tg-cynog-MP1854-Ab-2
Products NameAnti-TNFRSF10C monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TNFRSF10C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.