human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 4(WNT4) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 4 (WNT4) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

WNT4 is a secreted protein that in humans is encoded by the Wnt4 gene, found on chromosome 1. It promotes female sex development and represses male sex development. Loss of function can have serious consequences, such as female to male sex reversal. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and embryogenesis.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-MP1936-Ag-1wingless-type MMTV integration site family, member 4 (WNT4) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP1936-Ab-1Anti-WNT4 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP1936-Ab-2Anti-WNT4 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1936-Ag-1wingless-type MMTV integration site family, member 4 (WNT4)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1936-Ab-1Anti-WNT4 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP1936-Ab-2Anti-WNT4 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1936-Ag-1wingless-type MMTV integration site family, member 4 (WNT4)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1936-Ab-1Anti-WNT4 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP1936-Ab-2Anti-WNT4 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1936-Ag-1wingless-type MMTV integration site family, member 4 (WNT4)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1936-Ab-1Anti-WNT4 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP1936-Ab-2Anti-WNT4 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameWNT4
Full namewingless-type MMTV integration site family, member 4
Gene ID54361
Gene NameWNT4
Gene AliasSERKAL, WNT-4
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-MP1936-Ag-1, GM-Tg-rg-MP1936-Ag-1, GM-Tg-mg-MP1936-Ag-1, GM-Tg-cynog-MP1936-Ag-1
Products Namewingless-type MMTV integration site family, member 4 (WNT4) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 4 (WNT4) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-MP1936-Ab-1, GM-Tg-hg-MP1936-Ab-2,
GM-Tg-rg-MP1936-Ab-1, GM-Tg-rg-MP1936-Ab-2,
GM-Tg-mg-MP1936-Ab-1, GM-Tg-mg-MP1936-Ab-2,
GM-Tg-cynog-MP1936-Ab-1, GM-Tg-cynog-MP1936-Ab-2
Products NameAnti-WNT4 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WNT4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.