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human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 6(WNT6) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to WNT6/WNT6 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 6 (WNT6) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Wingless-type MMTV integration site family, member 6, also known as WNT6, is a human gene.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, which are involved in the Wnt signaling pathway. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-MP1938-Ag-1 | wingless-type MMTV integration site family, member 6 (WNT6) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP1938-Ab-1 | Anti-WNT6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-MP1938-Ab-2 | Anti-WNT6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP1938-Ag-1 | wingless-type MMTV integration site family, member 6 (WNT6) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP1938-Ab-1 | Anti-WNT6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-MP1938-Ab-2 | Anti-WNT6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP1938-Ag-1 | wingless-type MMTV integration site family, member 6 (WNT6) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP1938-Ab-1 | Anti-WNT6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-MP1938-Ab-2 | Anti-WNT6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP1938-Ag-1 | wingless-type MMTV integration site family, member 6 (WNT6) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP1938-Ab-1 | Anti-WNT6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-MP1938-Ab-2 | Anti-WNT6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | WNT6 |
| Full name | wingless-type MMTV integration site family, member 6 |
| Gene ID | 7475 |
| Gene Name | WNT6 |
| Gene Alias | |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-MP1938-Ag-1, GM-Tg-rg-MP1938-Ag-1, GM-Tg-mg-MP1938-Ag-1, GM-Tg-cynog-MP1938-Ag-1 |
| Products Name | wingless-type MMTV integration site family, member 6 (WNT6) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 6 (WNT6) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-MP1938-Ab-1, GM-Tg-hg-MP1938-Ab-2, GM-Tg-rg-MP1938-Ab-1, GM-Tg-rg-MP1938-Ab-2, GM-Tg-mg-MP1938-Ab-1, GM-Tg-mg-MP1938-Ab-2, GM-Tg-cynog-MP1938-Ab-1, GM-Tg-cynog-MP1938-Ab-2 |
| Products Name | Anti-WNT6 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WNT6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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