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human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 4(IGFBP4) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IGFBP4/IGFBP4 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 4 (IGFBP4) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4 gene.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP-4 is a unique protein and it consistently inhibits several cancer cells in vivo and in vitro. Its inhibitory action has been shown in vivo in prostate and colon. It is secreted by all colon cancer cells.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-SE0986-Ag-1 | insulin-like growth factor binding protein 4 (IGFBP4) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0986-Ab-1 | Anti-IGFBP4 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0986-Ab-2 | Anti-IGFBP4 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0986-Ag-1 | insulin-like growth factor binding protein 4 (IGFBP4) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0986-Ab-1 | Anti-IGFBP4 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0986-Ab-2 | Anti-IGFBP4 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0986-Ag-1 | insulin-like growth factor binding protein 4 (IGFBP4) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0986-Ab-1 | Anti-IGFBP4 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0986-Ab-2 | Anti-IGFBP4 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0986-Ag-1 | insulin-like growth factor binding protein 4 (IGFBP4) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0986-Ab-1 | Anti-IGFBP4 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0986-Ab-2 | Anti-IGFBP4 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IGFBP4 |
| Full name | insulin-like growth factor binding protein 4 |
| Gene ID | 3487 |
| Gene Name | IGFBP4 |
| Gene Alias | BP-4, HT29-IGFBP, IBP4, IGFBP-4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-SE0986-Ag-1, GM-Tg-rg-SE0986-Ag-1, GM-Tg-mg-SE0986-Ag-1, GM-Tg-cynog-SE0986-Ag-1 |
| Products Name | insulin-like growth factor binding protein 4 (IGFBP4) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 4 (IGFBP4) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-SE0986-Ab-1, GM-Tg-hg-SE0986-Ab-2, GM-Tg-rg-SE0986-Ab-1, GM-Tg-rg-SE0986-Ab-2, GM-Tg-mg-SE0986-Ab-1, GM-Tg-mg-SE0986-Ab-2, GM-Tg-cynog-SE0986-Ab-1, GM-Tg-cynog-SE0986-Ab-2 |
| Products Name | Anti-IGFBP4 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IGFBP4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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