human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 36, beta(IL36B) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 36, beta (IL36B) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interleukin-36 beta also known as interleukin-1 family member 8 (IL1F8) is a protein that in humans is encoded by the IL36B gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-SE1030-Ag-1interleukin 36, beta (IL36B) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1030-Ab-1Anti-IL36B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1030-Ab-2Anti-IL36B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1030-Ag-1interleukin 36, beta (IL36B)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1030-Ab-1Anti-IL36B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1030-Ab-2Anti-IL36B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1030-Ag-1interleukin 36, beta (IL36B)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1030-Ab-1Anti-IL36B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1030-Ab-2Anti-IL36B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1030-Ag-1interleukin 36, beta (IL36B)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1030-Ab-1Anti-IL36B monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1030-Ab-2Anti-IL36B monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIL36B
Full nameinterleukin 36, beta
Gene ID27177
Gene NameIL36B
Gene AliasFIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-SE1030-Ag-1, GM-Tg-rg-SE1030-Ag-1, GM-Tg-mg-SE1030-Ag-1, GM-Tg-cynog-SE1030-Ag-1
Products Nameinterleukin 36, beta (IL36B) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 36, beta (IL36B) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-SE1030-Ab-1, GM-Tg-hg-SE1030-Ab-2,
GM-Tg-rg-SE1030-Ab-1, GM-Tg-rg-SE1030-Ab-2,
GM-Tg-mg-SE1030-Ab-1, GM-Tg-mg-SE1030-Ab-2,
GM-Tg-cynog-SE1030-Ab-1, GM-Tg-cynog-SE1030-Ab-2
Products NameAnti-IL36B monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL36B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.