human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8A(WNT8A) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8A (WNT8A) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The Wnt signaling pathway has wide range of functional properties ranging from cell proliferation and tissue homeostasis to cell differentiation and cellular diversity in development and disease. Wnt8A belongs to the Wnt family of secreted signaling proteins and is a ligand for members of the frizzled family of seven transmembrane receptors. These have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.
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Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
GM-Tg-hg-SE1384-Ag-1 | wingless-type MMTV integration site family, member 8A (WNT8A) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-SE1384-Ab-1 | Anti-WNT8A monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-SE1384-Ab-2 | Anti-WNT8A monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE1384-Ag-1 | wingless-type MMTV integration site family, member 8A (WNT8A) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE1384-Ab-1 | Anti-WNT8A monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-SE1384-Ab-2 | Anti-WNT8A monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE1384-Ag-1 | wingless-type MMTV integration site family, member 8A (WNT8A) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE1384-Ab-1 | Anti-WNT8A monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-SE1384-Ab-2 | Anti-WNT8A monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE1384-Ag-1 | wingless-type MMTV integration site family, member 8A (WNT8A) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE1384-Ab-1 | Anti-WNT8A monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-SE1384-Ab-2 | Anti-WNT8A monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Target Information
Target Name | WNT8A |
Full name | wingless-type MMTV integration site family, member 8A |
Gene ID | 7478 |
Gene Name | WNT8A |
Gene Alias | WNT8D |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
Cat No. | GM-Tg-hg-SE1384-Ag-1, GM-Tg-rg-SE1384-Ag-1, GM-Tg-mg-SE1384-Ag-1, GM-Tg-cynog-SE1384-Ag-1 |
Products Name | wingless-type MMTV integration site family, member 8A (WNT8A) protein |
Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
Tag | His |
Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8A (WNT8A) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
Catalog No. | GM-Tg-hg-SE1384-Ab-1, GM-Tg-hg-SE1384-Ab-2, GM-Tg-rg-SE1384-Ab-1, GM-Tg-rg-SE1384-Ab-2, GM-Tg-mg-SE1384-Ab-1, GM-Tg-mg-SE1384-Ab-2, GM-Tg-cynog-SE1384-Ab-1, GM-Tg-cynog-SE1384-Ab-2 |
Products Name | Anti-WNT8A monoclonal antibody |
Format | mab |
Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-WNT8A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |