human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide(PDGFA) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide (PDGFA) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T06869-Ag-1platelet-derived growth factor alpha polypeptide (PDGFA) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T06869-Ab-1Anti-PDGFA monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T06869-Ab-2Anti-PDGFA monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T06869-Ag-1platelet-derived growth factor alpha polypeptide (PDGFA)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T06869-Ab-1Anti-PDGFA monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T06869-Ab-2Anti-PDGFA monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T06869-Ag-1platelet-derived growth factor alpha polypeptide (PDGFA)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T06869-Ab-1Anti-PDGFA monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T06869-Ab-2Anti-PDGFA monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T06869-Ag-1platelet-derived growth factor alpha polypeptide (PDGFA)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T06869-Ab-1Anti-PDGFA monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T06869-Ab-2Anti-PDGFA monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NamePDGFA
Full nameplatelet-derived growth factor alpha polypeptide
Gene ID5154
Gene NamePDGFA
Gene AliasPDGF-A, PDGF1
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T06869-Ag-1, GM-Tg-rg-T06869-Ag-1, GM-Tg-mg-T06869-Ag-1, GM-Tg-cynog-T06869-Ag-1
Products Nameplatelet-derived growth factor alpha polypeptide (PDGFA) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide (PDGFA) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T06869-Ab-1, GM-Tg-hg-T06869-Ab-2,
GM-Tg-rg-T06869-Ab-1, GM-Tg-rg-T06869-Ab-2,
GM-Tg-mg-T06869-Ab-1, GM-Tg-mg-T06869-Ab-2,
GM-Tg-cynog-T06869-Ab-1, GM-Tg-cynog-T06869-Ab-2
Products NameAnti-PDGFA monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PDGFA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.