human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta(KLB) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta (KLB) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

KLB (Klotho Beta) is a Protein Coding gene. Diseases associated with KLB include Outlet Dysfunction Constipation and Functional Diarrhea. Among its related pathways are RET signaling and PI3K/AKT activation. Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T14110-Ag-1klotho beta (KLB) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T14110-Ab-1Anti-KLB monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T14110-Ab-2Anti-KLB monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14110-Ag-1klotho beta (KLB)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14110-Ab-1Anti-KLB monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14110-Ab-2Anti-KLB monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14110-Ag-1klotho beta (KLB)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14110-Ab-1Anti-KLB monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14110-Ab-2Anti-KLB monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14110-Ag-1klotho beta (KLB)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14110-Ab-1Anti-KLB monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14110-Ab-2Anti-KLB monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameKLB
Full nameklotho beta
Gene ID152831
Gene NameKLB
Gene AliasBKL
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-T14110-Ag-1, GM-Tg-rg-T14110-Ag-1, GM-Tg-mg-T14110-Ag-1, GM-Tg-cynog-T14110-Ag-1
Products Nameklotho beta (KLB) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta (KLB) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T14110-Ab-1, GM-Tg-hg-T14110-Ab-2,
GM-Tg-rg-T14110-Ab-1, GM-Tg-rg-T14110-Ab-2,
GM-Tg-mg-T14110-Ab-1, GM-Tg-mg-T14110-Ab-2,
GM-Tg-cynog-T14110-Ab-1, GM-Tg-cynog-T14110-Ab-2
Products NameAnti-KLB monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KLB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.