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human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta(KLB) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to KLB/KLB products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta (KLB) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
KLB (Klotho Beta) is a Protein Coding gene. Diseases associated with KLB include Outlet Dysfunction Constipation and Functional Diarrhea. Among its related pathways are RET signaling and PI3K/AKT activation. Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T14110-Ag-1 | klotho beta (KLB) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T14110-Ab-1 | Anti-KLB monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T14110-Ab-2 | Anti-KLB monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14110-Ag-1 | klotho beta (KLB) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14110-Ab-1 | Anti-KLB monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14110-Ab-2 | Anti-KLB monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14110-Ag-1 | klotho beta (KLB) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14110-Ab-1 | Anti-KLB monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14110-Ab-2 | Anti-KLB monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14110-Ag-1 | klotho beta (KLB) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14110-Ab-1 | Anti-KLB monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14110-Ab-2 | Anti-KLB monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | KLB |
| Full name | klotho beta |
| Gene ID | 152831 |
| Gene Name | KLB |
| Gene Alias | BKL |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T14110-Ag-1, GM-Tg-rg-T14110-Ag-1, GM-Tg-mg-T14110-Ag-1, GM-Tg-cynog-T14110-Ag-1 |
| Products Name | klotho beta (KLB) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse klotho beta (KLB) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T14110-Ab-1, GM-Tg-hg-T14110-Ab-2, GM-Tg-rg-T14110-Ab-1, GM-Tg-rg-T14110-Ab-2, GM-Tg-mg-T14110-Ab-1, GM-Tg-mg-T14110-Ab-2, GM-Tg-cynog-T14110-Ab-1, GM-Tg-cynog-T14110-Ab-2 |
| Products Name | Anti-KLB monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-KLB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
