human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta(IL10RB) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta (IL10RB) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene. IL10RB has also recently been designated CDW210B (cluster of differentiation W210B). The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T14557-Ag-1interleukin 10 receptor, beta (IL10RB) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T14557-Ab-1Anti-IL10RB monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T14557-Ab-2Anti-IL10RB monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14557-Ag-1interleukin 10 receptor, beta (IL10RB)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14557-Ab-1Anti-IL10RB monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T14557-Ab-2Anti-IL10RB monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14557-Ag-1interleukin 10 receptor, beta (IL10RB)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14557-Ab-1Anti-IL10RB monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T14557-Ab-2Anti-IL10RB monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14557-Ag-1interleukin 10 receptor, beta (IL10RB)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14557-Ab-1Anti-IL10RB monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T14557-Ab-2Anti-IL10RB monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIL10RB
Full nameinterleukin 10 receptor, beta
Gene ID3588
Gene NameIL10RB
Gene AliasCDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-T14557-Ag-1, GM-Tg-rg-T14557-Ag-1, GM-Tg-mg-T14557-Ag-1, GM-Tg-cynog-T14557-Ag-1
Products Nameinterleukin 10 receptor, beta (IL10RB) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta (IL10RB) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T14557-Ab-1, GM-Tg-hg-T14557-Ab-2,
GM-Tg-rg-T14557-Ab-1, GM-Tg-rg-T14557-Ab-2,
GM-Tg-mg-T14557-Ab-1, GM-Tg-mg-T14557-Ab-2,
GM-Tg-cynog-T14557-Ab-1, GM-Tg-cynog-T14557-Ab-2
Products NameAnti-IL10RB monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL10RB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.