human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 1(IGFBP1) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 1 (IGFBP1) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. This gene is a member of the Insulin-like growth factor-binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T15048-Ag-1insulin-like growth factor binding protein 1 (IGFBP1) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T15048-Ab-1Anti-IGFBP1 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T15048-Ab-2Anti-IGFBP1 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T15048-Ag-1insulin-like growth factor binding protein 1 (IGFBP1)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T15048-Ab-1Anti-IGFBP1 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T15048-Ab-2Anti-IGFBP1 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T15048-Ag-1insulin-like growth factor binding protein 1 (IGFBP1)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T15048-Ab-1Anti-IGFBP1 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T15048-Ab-2Anti-IGFBP1 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T15048-Ag-1insulin-like growth factor binding protein 1 (IGFBP1)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T15048-Ab-1Anti-IGFBP1 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T15048-Ab-2Anti-IGFBP1 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIGFBP1
Full nameinsulin-like growth factor binding protein 1
Gene ID3484
Gene NameIGFBP1
Gene AliasAFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T15048-Ag-1, GM-Tg-rg-T15048-Ag-1, GM-Tg-mg-T15048-Ag-1, GM-Tg-cynog-T15048-Ag-1
Products Nameinsulin-like growth factor binding protein 1 (IGFBP1) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse insulin-like growth factor binding protein 1 (IGFBP1) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T15048-Ab-1, GM-Tg-hg-T15048-Ab-2,
GM-Tg-rg-T15048-Ab-1, GM-Tg-rg-T15048-Ab-2,
GM-Tg-mg-T15048-Ab-1, GM-Tg-mg-T15048-Ab-2,
GM-Tg-cynog-T15048-Ab-1, GM-Tg-cynog-T15048-Ab-2
Products NameAnti-IGFBP1 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGFBP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.