Products
human, Cynomolgus/ Rhesus macaque, rat, mouse TNF receptor-associated factor 6, E3 ubiquitin protein ligase(TRAF6) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to TRAF6/TRAF6 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. This protein mediates the signaling from TNF receptor superfamily and Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/TRANCE/RANKL and IL-1 have been shown to be mediated by this protein. It interacts with various protein kinases such as IRAK1/IRAK, SRC and PKCzeta, to link the different signaling pathways. It acts as a signal transducer in the NF-kappaB pathway and activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T15051-Ag-1 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T15051-Ab-1 | Anti-TRAF6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T15051-Ab-2 | Anti-TRAF6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T15051-Ag-1 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T15051-Ab-1 | Anti-TRAF6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T15051-Ab-2 | Anti-TRAF6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T15051-Ag-1 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T15051-Ab-1 | Anti-TRAF6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T15051-Ab-2 | Anti-TRAF6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T15051-Ag-1 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T15051-Ab-1 | Anti-TRAF6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T15051-Ab-2 | Anti-TRAF6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | TRAF6 |
| Full name | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| Gene ID | 7189 |
| Gene Name | TRAF6 |
| Gene Alias | MGC:3310, RNF85 |
| Protein Sub-location | Introcelluar Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T15051-Ag-1, GM-Tg-rg-T15051-Ag-1, GM-Tg-mg-T15051-Ag-1, GM-Tg-cynog-T15051-Ag-1 |
| Products Name | TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse TNF receptor-associated factor 6, E3 ubiquitin protein ligase (TRAF6) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T15051-Ab-1, GM-Tg-hg-T15051-Ab-2, GM-Tg-rg-T15051-Ab-1, GM-Tg-rg-T15051-Ab-2, GM-Tg-mg-T15051-Ab-1, GM-Tg-mg-T15051-Ab-2, GM-Tg-cynog-T15051-Ab-1, GM-Tg-cynog-T15051-Ab-2 |
| Products Name | Anti-TRAF6 monoclonal antibody |
| Format | mab |
| Category of antibody | Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TRAF6 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Facebook
LinkedIn
Twitter
