human, Cynomolgus/ Rhesus macaque, rat, mouse oncostatin M(OSM) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse oncostatin M (OSM) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Oncostatin M, also known as OSM, is a protein that in humans is encoded by the OSM gene. OSM is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T19556-Ag-1oncostatin M (OSM) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T19556-Ab-1Anti-OSM monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T19556-Ab-2Anti-OSM monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T19556-Ag-1oncostatin M (OSM)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T19556-Ab-1Anti-OSM monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T19556-Ab-2Anti-OSM monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T19556-Ag-1oncostatin M (OSM)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T19556-Ab-1Anti-OSM monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T19556-Ab-2Anti-OSM monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T19556-Ag-1oncostatin M (OSM)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T19556-Ab-1Anti-OSM monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T19556-Ab-2Anti-OSM monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameOSM
Full nameoncostatin M
Gene ID5008
Gene NameOSM
Gene Alias
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T19556-Ag-1, GM-Tg-rg-T19556-Ag-1, GM-Tg-mg-T19556-Ag-1, GM-Tg-cynog-T19556-Ag-1
Products Nameoncostatin M (OSM) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse oncostatin M (OSM) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T19556-Ab-1, GM-Tg-hg-T19556-Ab-2,
GM-Tg-rg-T19556-Ab-1, GM-Tg-rg-T19556-Ab-2,
GM-Tg-mg-T19556-Ab-1, GM-Tg-mg-T19556-Ab-2,
GM-Tg-cynog-T19556-Ab-1, GM-Tg-cynog-T19556-Ab-2
Products NameAnti-OSM monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OSM benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.