human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4(FGF4) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4 (FGF4) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T28076-Ag-1fibroblast growth factor 4 (FGF4) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T28076-Ab-1Anti-FGF4 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T28076-Ab-2Anti-FGF4 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T28076-Ag-1fibroblast growth factor 4 (FGF4)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T28076-Ab-1Anti-FGF4 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T28076-Ab-2Anti-FGF4 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T28076-Ag-1fibroblast growth factor 4 (FGF4)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T28076-Ab-1Anti-FGF4 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T28076-Ab-2Anti-FGF4 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T28076-Ag-1fibroblast growth factor 4 (FGF4)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T28076-Ab-1Anti-FGF4 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T28076-Ab-2Anti-FGF4 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameFGF4
Full namefibroblast growth factor 4
Gene ID2249
Gene NameFGF4
Gene AliasFGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T28076-Ag-1, GM-Tg-rg-T28076-Ag-1, GM-Tg-mg-T28076-Ag-1, GM-Tg-cynog-T28076-Ag-1
Products Namefibroblast growth factor 4 (FGF4) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4 (FGF4) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T28076-Ab-1, GM-Tg-hg-T28076-Ab-2,
GM-Tg-rg-T28076-Ab-1, GM-Tg-rg-T28076-Ab-2,
GM-Tg-mg-T28076-Ab-1, GM-Tg-mg-T28076-Ab-2,
GM-Tg-cynog-T28076-Ab-1, GM-Tg-cynog-T28076-Ab-2
Products NameAnti-FGF4 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FGF4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.