human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4(FGF4) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4 (FGF4) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Fibroblast growth factor 4 is a protein that in humans is encoded by the FGF4 gene.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
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Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
GM-Tg-hg-T28076-Ag-1 | fibroblast growth factor 4 (FGF4) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T28076-Ab-1 | Anti-FGF4 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T28076-Ab-2 | Anti-FGF4 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T28076-Ag-1 | fibroblast growth factor 4 (FGF4) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T28076-Ab-1 | Anti-FGF4 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T28076-Ab-2 | Anti-FGF4 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T28076-Ag-1 | fibroblast growth factor 4 (FGF4) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T28076-Ab-1 | Anti-FGF4 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T28076-Ab-2 | Anti-FGF4 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T28076-Ag-1 | fibroblast growth factor 4 (FGF4) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T28076-Ab-1 | Anti-FGF4 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T28076-Ab-2 | Anti-FGF4 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Target Information
Target Name | FGF4 |
Full name | fibroblast growth factor 4 |
Gene ID | 2249 |
Gene Name | FGF4 |
Gene Alias | FGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
Cat No. | GM-Tg-hg-T28076-Ag-1, GM-Tg-rg-T28076-Ag-1, GM-Tg-mg-T28076-Ag-1, GM-Tg-cynog-T28076-Ag-1 |
Products Name | fibroblast growth factor 4 (FGF4) protein |
Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
Tag | His |
Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor 4 (FGF4) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
Catalog No. | GM-Tg-hg-T28076-Ab-1, GM-Tg-hg-T28076-Ab-2, GM-Tg-rg-T28076-Ab-1, GM-Tg-rg-T28076-Ab-2, GM-Tg-mg-T28076-Ab-1, GM-Tg-mg-T28076-Ab-2, GM-Tg-cynog-T28076-Ab-1, GM-Tg-cynog-T28076-Ab-2 |
Products Name | Anti-FGF4 monoclonal antibody |
Format | mab |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-FGF4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |