Products
human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3(SMAD3) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to SMAD3/SMAD3 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3 (SMAD3) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene.
SMAD3 is a member of the SMAD family of proteins. It acts as a mediator of the signals initiated by the transforming growth factor beta (TGF-β) superfamily of cytokines, which regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T35445-Ag-1 | SMAD family member 3 (SMAD3) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ag-1 | SMAD family member 3 (SMAD3) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ag-1 | SMAD family member 3 (SMAD3) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ag-1 | SMAD family member 3 (SMAD3) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | SMAD3 |
| Full name | SMAD family member 3 |
| Gene ID | 4088 |
| Gene Name | SMAD3 |
| Gene Alias | HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 |
| Protein Sub-location | Introcelluar Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T35445-Ag-1, GM-Tg-rg-T35445-Ag-1, GM-Tg-mg-T35445-Ag-1, GM-Tg-cynog-T35445-Ag-1 |
| Products Name | SMAD family member 3 (SMAD3) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3 (SMAD3) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T35445-Ab-1, GM-Tg-hg-T35445-Ab-2, GM-Tg-rg-T35445-Ab-1, GM-Tg-rg-T35445-Ab-2, GM-Tg-mg-T35445-Ab-1, GM-Tg-mg-T35445-Ab-2, GM-Tg-cynog-T35445-Ab-1, GM-Tg-cynog-T35445-Ab-2 |
| Products Name | Anti-SMAD3 monoclonal antibody |
| Format | mab |
| Category of antibody | Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SMAD3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Facebook
LinkedIn
Twitter
