human, Cynomolgus/ Rhesus macaque, rat, mouse Interleukin-1 Beta(Il1b) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse Interleukin-1 Beta (Il1b) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interleukin 1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1β.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T42000-Ag-1Interleukin-1 Beta (Il1b) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T42000-Ab-1Anti-Il1b monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T42000-Ab-2Anti-Il1b monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T42000-Ag-1Interleukin-1 Beta (Il1b)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T42000-Ab-1Anti-Il1b monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T42000-Ab-2Anti-Il1b monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T42000-Ag-1Interleukin-1 Beta (Il1b)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T42000-Ab-1Anti-Il1b monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T42000-Ab-2Anti-Il1b monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T42000-Ag-1Interleukin-1 Beta (Il1b)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T42000-Ab-1Anti-Il1b monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T42000-Ab-2Anti-Il1b monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIl1b
Full nameInterleukin-1 Beta
Gene ID3553
Gene NameIl1b
Gene AliasIL-1, IL1-BETA, IL1F2
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T42000-Ag-1, GM-Tg-rg-T42000-Ag-1, GM-Tg-mg-T42000-Ag-1, GM-Tg-cynog-T42000-Ag-1
Products NameInterleukin-1 Beta (Il1b) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse Interleukin-1 Beta (Il1b) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T42000-Ab-1, GM-Tg-hg-T42000-Ab-2,
GM-Tg-rg-T42000-Ab-1, GM-Tg-rg-T42000-Ab-2,
GM-Tg-mg-T42000-Ab-1, GM-Tg-mg-T42000-Ab-2,
GM-Tg-cynog-T42000-Ab-1, GM-Tg-cynog-T42000-Ab-2
Products NameAnti-IL1B monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.