human, Cynomolgus/ Rhesus macaque, rat, mouse IFNA2 interferon, alpha 2(IFNA2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


Target products collectionGo to IFNA2/IFNA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse IFNA2 interferon, alpha 2 (IFNA2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. The broad spectrum of ISGs explains the wide range of biological activity of type I IFNs. In addition to their antiviral activity, type I IFNs also inhibit the proliferation of cells and regulate the activation of the immune system. Type I IFNs exert potent antitumor activity by several mechanisms such as: inhibition of the proliferation of cancer cells activation of the immune system which can eliminate tumor cells increasing the antitumor activity of other antitumoral agents (radiotherapy, chemotherapy, targeted therapies) Type I IFNs can have detrimental effects during viral and non-viral infections (bacterial, parasitic, fungal). This is due in part by the ability of type I IFNs to polarize the immune system towards a specific type of response in order to interfere with virus infections. When improperly regulated, IFN production or IFN-induced signalling can result in autoimmune diseases, such as systemic lupus erythematosus.


Order information


* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry

Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T63934-Ag-1IFNA2 interferon, alpha 2 (IFNA2) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T63934-Ab-1Anti-IFNA2 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T63934-Ab-2Anti-IFNA2 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T63934-Ag-1IFNA2 interferon, alpha 2 (IFNA2)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T63934-Ab-1Anti-IFNA2 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T63934-Ab-2Anti-IFNA2 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T63934-Ag-1IFNA2 interferon, alpha 2 (IFNA2)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T63934-Ab-1Anti-IFNA2 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T63934-Ab-2Anti-IFNA2 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T63934-Ag-1IFNA2 interferon, alpha 2 (IFNA2)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T63934-Ab-1Anti-IFNA2 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T63934-Ab-2Anti-IFNA2 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameIFNA2
Full nameIFNA2 interferon, alpha 2
Gene ID3440
Gene NameIFNA2
Gene AliasIFN-alphaA, IFNAB, INFA2, IFNA2
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T63934-Ag-1, GM-Tg-rg-T63934-Ag-1, GM-Tg-mg-T63934-Ag-1, GM-Tg-cynog-T63934-Ag-1
Products NameIFNA2 interferon, alpha 2 (IFNA2) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse IFNA2 interferon, alpha 2 (IFNA2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T63934-Ab-1, GM-Tg-hg-T63934-Ab-2,
GM-Tg-rg-T63934-Ab-1, GM-Tg-rg-T63934-Ab-2,
GM-Tg-mg-T63934-Ab-1, GM-Tg-mg-T63934-Ab-2,
GM-Tg-cynog-T63934-Ab-1, GM-Tg-cynog-T63934-Ab-2
Products NameAnti-IFNA2 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IFNA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.