human, Cynomolgus/ Rhesus macaque, rat, mouse CD70 antigen(CD70) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse CD70 antigen (CD70) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. CD70 is a ligand for CD27. The CD70 protein is expressed on highly activated lymphocytes (like in T- and B-cell lymphomas). It is therefore suggested that anti-CD70 antibodies might be a possible treatment for CD70 positive lymphomas as normal lymphocytes have low CD70 expression.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T67805-Ag-1CD70 antigen (CD70) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T67805-Ab-1Anti-CD70 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T67805-Ab-2Anti-CD70 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T67805-Ag-1CD70 antigen (CD70)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T67805-Ab-1Anti-CD70 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T67805-Ab-2Anti-CD70 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T67805-Ag-1CD70 antigen (CD70)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T67805-Ab-1Anti-CD70 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T67805-Ab-2Anti-CD70 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T67805-Ag-1CD70 antigen (CD70)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T67805-Ab-1Anti-CD70 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T67805-Ab-2Anti-CD70 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameCD70
Full nameCD70 antigen
Gene ID970
Gene NameCD70
Gene AliasCD27-L, CD27L, CD27LG, TNFSF7, TNLG8A
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-T67805-Ag-1, GM-Tg-rg-T67805-Ag-1, GM-Tg-mg-T67805-Ag-1, GM-Tg-cynog-T67805-Ag-1
Products NameCD70 antigen (CD70) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse CD70 antigen (CD70) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T67805-Ab-1, GM-Tg-hg-T67805-Ab-2,
GM-Tg-rg-T67805-Ab-1, GM-Tg-rg-T67805-Ab-2,
GM-Tg-mg-T67805-Ab-1, GM-Tg-mg-T67805-Ab-2,
GM-Tg-cynog-T67805-Ab-1, GM-Tg-cynog-T67805-Ab-2
Products NameAnti-CD27-L/CD70 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CD27-L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.