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human, Cynomolgus/ Rhesus macaque, rat, mouse WNT1 inducible signaling pathway protein 1(WISP1) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to WISP1/CCN4 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse WNT1 inducible signaling pathway protein 1 (WISP1) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
WNT1-inducible-signaling pathway protein 1 (WISP-1), also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene.
WISP-1 is highly homologous to CYR61 (CCN1) and CTGF (CCN2), and is a member of the CCN family of secreted, extracellular matrix (ECM)-associated signaling proteins (CCN intercellular signaling protein). The CCN family of proteins shares a common molecular protein structure, characterized by an N-terminal secretory signal peptide followed by four distinct domains with homologies to insulin-like growth factor binding protein (IGFBP), von Willebrand type C repeats (vWC), thrombospondin type 1 repeat (TSR), and a cysteine knot motif within the C-terminal (CT) domain. This family of proteins regulates diverse cellular functions, including cell adhesion, migration, proliferation, differentiation, and survival.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T71859-Ag-1 | WNT1 inducible signaling pathway protein 1 (WISP1) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T71859-Ab-1 | Anti-WISP1 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T71859-Ab-2 | Anti-WISP1 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T71859-Ag-1 | WNT1 inducible signaling pathway protein 1 (WISP1) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T71859-Ab-1 | Anti-WISP1 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T71859-Ab-2 | Anti-WISP1 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T71859-Ag-1 | WNT1 inducible signaling pathway protein 1 (WISP1) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T71859-Ab-1 | Anti-WISP1 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T71859-Ab-2 | Anti-WISP1 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T71859-Ag-1 | WNT1 inducible signaling pathway protein 1 (WISP1) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T71859-Ab-1 | Anti-WISP1 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T71859-Ab-2 | Anti-WISP1 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | WISP1 |
| Full name | WNT1 inducible signaling pathway protein 1 |
| Gene ID | 8840 |
| Gene Name | WISP1 |
| Gene Alias | WISP1, WISP1-OT1, WISP1-UT1, WISP1c, WISP1i, WISP1tc |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T71859-Ag-1, GM-Tg-rg-T71859-Ag-1, GM-Tg-mg-T71859-Ag-1, GM-Tg-cynog-T71859-Ag-1 |
| Products Name | WNT1 inducible signaling pathway protein 1 (WISP1) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse WNT1 inducible signaling pathway protein 1 (WISP1) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T71859-Ab-1, GM-Tg-hg-T71859-Ab-2, GM-Tg-rg-T71859-Ab-1, GM-Tg-rg-T71859-Ab-2, GM-Tg-mg-T71859-Ab-1, GM-Tg-mg-T71859-Ab-2, GM-Tg-cynog-T71859-Ab-1, GM-Tg-cynog-T71859-Ab-2 |
| Products Name | Anti-WISP1/CCN4 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WISP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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