human, Cynomolgus/ Rhesus macaque, rat, mouse epiregulin(EREG) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse epiregulin (EREG) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. Epiregulin is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T79157-Ag-1epiregulin (EREG) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T79157-Ab-1Anti-EREG monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T79157-Ab-2Anti-EREG monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79157-Ag-1epiregulin (EREG)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79157-Ab-1Anti-EREG monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79157-Ab-2Anti-EREG monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79157-Ag-1epiregulin (EREG)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79157-Ab-1Anti-EREG monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79157-Ab-2Anti-EREG monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79157-Ag-1epiregulin (EREG)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79157-Ab-1Anti-EREG monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79157-Ab-2Anti-EREG monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameEREG
Full nameepiregulin
Gene ID2069
Gene NameEREG
Gene AliasEPR, ER, Ep
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T79157-Ag-1, GM-Tg-rg-T79157-Ag-1, GM-Tg-mg-T79157-Ag-1, GM-Tg-cynog-T79157-Ag-1
Products Nameepiregulin (EREG) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse epiregulin (EREG) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T79157-Ab-1, GM-Tg-hg-T79157-Ab-2,
GM-Tg-rg-T79157-Ab-1, GM-Tg-rg-T79157-Ab-2,
GM-Tg-mg-T79157-Ab-1, GM-Tg-mg-T79157-Ab-2,
GM-Tg-cynog-T79157-Ab-1, GM-Tg-cynog-T79157-Ab-2
Products NameAnti-EREG monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EREG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.