human, Cynomolgus/ Rhesus macaque, rat, mouse leptin(LEP) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse leptin (LEP) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Leptin (from Greek λεπτός leptos, "thin") is a hormone predominantly made by adipose cells and enterocytes in the small intestine that helps to regulate energy balance by inhibiting hunger, which in turn diminishes fat storage in adipocytes. Leptin acts on cell receptors in the arcuate and ventromedial nuclei, as well as other parts of the hypothalamus and dopaminergic neurons of the ventral tegmental area, consequently mediating feeding.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T79485-Ag-1leptin (LEP) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T79485-Ab-1Anti-LEP monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T79485-Ab-2Anti-LEP monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79485-Ag-1leptin (LEP)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79485-Ab-1Anti-LEP monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T79485-Ab-2Anti-LEP monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79485-Ag-1leptin (LEP)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79485-Ab-1Anti-LEP monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T79485-Ab-2Anti-LEP monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79485-Ag-1leptin (LEP)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79485-Ab-1Anti-LEP monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T79485-Ab-2Anti-LEP monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameLEP
Full nameleptin
Gene ID3952
Gene NameLEP
Gene AliasLEPD, OB, OBS
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-T79485-Ag-1, GM-Tg-rg-T79485-Ag-1, GM-Tg-mg-T79485-Ag-1, GM-Tg-cynog-T79485-Ag-1
Products Nameleptin (LEP) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse leptin (LEP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T79485-Ab-1, GM-Tg-hg-T79485-Ab-2,
GM-Tg-rg-T79485-Ab-1, GM-Tg-rg-T79485-Ab-2,
GM-Tg-mg-T79485-Ab-1, GM-Tg-mg-T79485-Ab-2,
GM-Tg-cynog-T79485-Ab-1, GM-Tg-cynog-T79485-Ab-2
Products NameAnti-LEP monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LEP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.