human, Cynomolgus/ Rhesus macaque, rat, mouse erb-b2 receptor tyrosine kinase 3(ERBB3) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


Target products collectionGo to Erbb-3/ERBB3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse erb-b2 receptor tyrosine kinase 3 (ERBB3) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is encoded by the ERBB3 gene. ErbB3 is a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is known to form active heterodimers with other members of the ErbB family, most notably the ligand binding-impaired ErbB2.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-T86350-Ag-1erb-b2 receptor tyrosine kinase 3 (ERBB3) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T86350-Ab-1Anti-ERBB3 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T86350-Ab-2Anti-ERBB3 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T86350-Ag-1erb-b2 receptor tyrosine kinase 3 (ERBB3)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T86350-Ab-1Anti-ERBB3 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T86350-Ab-2Anti-ERBB3 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T86350-Ag-1erb-b2 receptor tyrosine kinase 3 (ERBB3)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T86350-Ab-1Anti-ERBB3 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T86350-Ab-2Anti-ERBB3 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T86350-Ag-1erb-b2 receptor tyrosine kinase 3 (ERBB3)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T86350-Ab-1Anti-ERBB3 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T86350-Ab-2Anti-ERBB3 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameERBB3
Full nameerb-b2 receptor tyrosine kinase 3
Gene ID2065
Gene NameERBB3
Gene AliasErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-T86350-Ag-1, GM-Tg-rg-T86350-Ag-1, GM-Tg-mg-T86350-Ag-1, GM-Tg-cynog-T86350-Ag-1
Products Nameerb-b2 receptor tyrosine kinase 3 (ERBB3) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse erb-b2 receptor tyrosine kinase 3 (ERBB3) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T86350-Ab-1, GM-Tg-hg-T86350-Ab-2,
GM-Tg-rg-T86350-Ab-1, GM-Tg-rg-T86350-Ab-2,
GM-Tg-mg-T86350-Ab-1, GM-Tg-mg-T86350-Ab-2,
GM-Tg-cynog-T86350-Ab-1, GM-Tg-cynog-T86350-Ab-2
Products NameAnti-Erbb-3/ERBB3 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-Erbb-3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.