Human UBE2B/E2-17kDa/HHR6B ORF/cDNA clone-Lentivirus particle (NM_003337)
Cat. No.: vGMLP000343
Pre-made Human UBE2B/E2-17kDa/HHR6B Lentiviral expression plasmid for UBE2B lentivirus packaging, UBE2B lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP000343 | Human UBE2B Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP000343 |
Gene Name | UBE2B |
Accession Number | NM_003337 |
Gene ID | 7320 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 459 bp |
Gene Alias | E2-17kDa,HHR6B,HR6B,RAD6B,UBC2 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGTCGACCCCGGCCCGGAGGAGGCTCATGCGGGATTTCAAGCGGTTACAAGAGGACCCACCTGTGGGTGTCAGTGGCGCACCATCTGAAAACAACATCATGCAGTGGAATGCAGTTATATTTGGACCAGAAGGGACACCTTTTGAAGATGGTACTTTTAAACTAGTAATAGAATTTTCTGAAGAATATCCAAATAAACCACCAACTGTTAGGTTTTTATCCAAAATGTTTCATCCAAATGTGTATGCTGATGGTAGCATATGTTTAGATATCCTTCAGAATCGATGGAGTCCAACATATGATGTATCTTCTATCTTAACATCAATTCAGTCTCTGCTGGATGAACCGAATCCTAACAGTCCAGCCAATAGCCAGGCAGCACAGCTTTATCAGGAAAACAAACGAGAATATGAGAAAAGAGTTTCGGCCATTGTTGAACAAAGCTGGAATGATTCATAA |
ORF Protein Sequence | MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-MP2371-Ab | Anti-UBE2B/ E2-17kDa/ HHR6B monoclonal antibody |
Target Antigen | GM-Tg-g-MP2371-Ag | UBE2B VLP (virus-like particle) |
ORF Viral Vector | pGMLP000343 | Human UBE2B Lentivirus plasmid |
ORF Viral Vector | vGMLP000343 | Human UBE2B Lentivirus particle |
Target information
Target ID | GM-MP2371 |
Target Name | UBE2B |
Gene ID | 7320, 22210, 710678, 81816, 101099525, 474683, 512207, 100062920 |
Gene Symbol and Synonyms | E2-14k,E2-17kDa,E214K,HHR6B,HR6B,mHR6B,RAD6B,UBC2,UBE2B |
Uniprot Accession | P63146 |
Uniprot Entry Name | UBE2B_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Not Available |
Disease | Not Available |
Gene Ensembl | ENSG00000119048 |
Target Classification | Not Available |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]
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