Human TREM2/TREM-2/Trem2a ORF/cDNA clone-Lentivirus particle (NM_018965)

Cat. No.: vGMLP003467

Pre-made Human TREM2/TREM-2/Trem2a Lentiviral expression plasmid for TREM2 lentivirus packaging, TREM2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collection

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP003467 Human TREM2 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP003467
Gene Name TREM2
Accession Number NM_018965
Gene ID 54209
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 693 bp
Gene Alias TREM-2,Trem2a,Trem2b,Trem2c
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGAGCCTCTCCGGCTGCTCATCTTACTCTTTGTCACAGAGCTGTCCGGAGCCCACAACACCACAGTGTTCCAGGGCGTGGCGGGCCAGTCCCTGCAGGTGTCTTGCCCCTATGACTCCATGAAGCACTGGGGGAGGCGCAAGGCCTGGTGCCGCCAGCTGGGAGAGAAGGGCCCATGCCAGCGTGTGGTCAGCACGCACAACTTGTGGCTGCTGTCCTTCCTGAGGAGGTGGAATGGGAGCACAGCCATCACAGACGATACCCTGGGTGGCACTCTCACCATTACGCTGCGGAATCTACAACCCCATGATGCGGGTCTCTACCAGTGCCAGAGCCTCCATGGCAGTGAGGCTGACACCCTCAGGAAGGTCCTGGTGGAGGTGCTGGCAGACCCCCTGGATCACCGGGATGCTGGAGATCTCTGGTTCCCCGGGGAGTCTGAGAGCTTCGAGGATGCCCATGTGGAGCACAGCATCTCCAGGAGCCTCTTGGAAGGAGAAATCCCCTTCCCACCCACTTCCATCCTTCTCCTCCTGGCCTGCATCTTTCTCATCAAGATTCTAGCAGCCAGCGCCCTCTGGGCTGCAGCCTGGCATGGACAGAAGCCAGGGACACATCCACCCAGTGAACTGGACTGTGGCCATGACCCAGGGTATCAGCTCCAAACTCTGCCAGGGCTGAGAGACACGTGA
ORF Protein Sequence MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASALWAAAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T45086-Ab Anti-TREM2/ TREM-2/ Trem2a monoclonal antibody
    Target Antigen GM-Tg-g-T45086-Ag TREM2 VLP (virus-like particle)
    ORF Viral Vector pGMLP003467 Human TREM2 Lentivirus plasmid
    ORF Viral Vector pGMAAV000622 Human TREM2 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP003467 Human TREM2 Lentivirus particle
    ORF Viral Vector vGMAAV000622 Human TREM2 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T45086
    Target Name TREM2
    Gene ID 54209, 83433, 719740, 301227, 101099297, 119863908, 506467, 100066180
    Gene Symbol and Synonyms LOC119863908,PLOSL2,TREM-2,TREM2,Trem2-Mia,Trem2-Mib,Trem2a,Trem2b,Trem2c
    Uniprot Accession Q9NZC2
    Uniprot Entry Name TREM2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000095970
    Target Classification Not Available

    This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]



    About GMVC

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