COVID-19 spike variants antigen Recombinant 2019-nCoV(SARS-CoV-2) Spike Protein S1 D614G mutant (S1-D614G,C-HisTag)

Cat No.: GMP-V-2019nCoV-Smu-001

Order information

Package Catalog No. Price(In USD) Qty (Quantity) Sum(In USD)
1mg GMP-V-2019nCoV-Smu-001-1mg 5990
10mg GMP-V-2019nCoV-Smu-001-10mg 38790
100mg GMP-V-2019nCoV-Smu-001-100mg 258000
≥100mg GMP-V-2019nCoV-Smu-001-xmg Inquiry
Shipping Cost: 760.00
Total:



Description

Accession Number QHD43415.1
Expression platform 2019-nCoV(SARS-CoV-2, SARS2-coronavirus)
IsotypesMamamlian (human cell)
TagC-His
Products descriptionRecombinant 2019-nCoV(SARS-CoV-2)e Spike Protein S1 domain with D614G mutant was expressed in mammanlian cell (human cells)expression system. The target gene encoding Gln14-Arg685(D614G) was expressed with HIS tag at the C-terminus.
Bioactivity validation ACE2 binding;
Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays;
PurityPurity: ≥95% (SDS-PAGE)
ApplicationSpike protein & ACE2 competition binding assay for efficacy evaluation of COVID-19 vaccines and therapeutic antibodies.
Immunogen in Elisa,lateral-flow tests,and other immunoassays;
Standard substance
The antigen can also be used in drug discovery including antibody screening and lead compound candidates assay.
predicted Molecular Mass76kDa
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

COVID-19 recombinant SARS-CoV2 (2019 nCoV coronavirus) antigen:
Recombinant 2019-nCoV(SARS-CoV-2) Spike Protein S1 D614G mutant (S1-D614G,C-HisTag).

Suitable for variants of Spike protein & ACE2 competition binding assay for efficacy evaluation of COVID-20 vaccines and therapeutic antibodies. Validated in functional ELISA, other immunoassays, the antigen can also be used in drug discovery including antibody screening and lead compound candidates assay.

The world is in midst of the COVID-19 pandemic caused by SARS-CoV-2 (2019nCoV) infection. The Spike protein (S-protein) of SARS-CoV-2 (2019nCoV) mediates receptor (ACE2) binding and cell entry and is the dominant target of the immune system. The D614G mutation in Spike S1 domain is proved to be a most important and popular mutant variant in Coronavirus SARS-CoV2.