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Anti-40S ribosomal protein S18 monoclonal antibody
Pre-made anti-40S ribosomal protein S18 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to 40S ribosomal protein S18/RPS18 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-INN060-Ab-1/ GM-Tg-hg-INN060-Ab-2 | Anti-Human 40S ribosomal protein S18/RPS18 monoclonal antibody | Human |
| GM-Tg-rg-INN060-Ab-1/ GM-Tg-rg-INN060-Ab-2 | Anti-Rat 40S ribosomal protein S18/RPS18 monoclonal antibody | Rat |
| GM-Tg-mg-INN060-Ab-1/ GM-Tg-mg-INN060-Ab-2 | Anti-Mouse 40S ribosomal protein S18/RPS18 monoclonal antibody | Mouse |
| GM-Tg-cynog-INN060-Ab-1/ GM-Tg-cynog-INN060-Ab-2 | Anti-Cynomolgus/ Rhesus macaque 40S ribosomal protein S18/RPS18 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-INN060-Ab-1/ GM-Tg-felg-INN060-Ab-2 | Anti-Feline 40S ribosomal protein S18/RPS18 monoclonal antibody | Feline |
| GM-Tg-cang-INN060-Ab-1/ GM-Tg-cang-INN060-Ab-2 | Anti-Canine 40S ribosomal protein S18/RPS18 monoclonal antibody | Canine |
| GM-Tg-bovg-INN060-Ab-1/ GM-Tg-bovg-INN060-Ab-2 | Anti-Bovine 40S ribosomal protein S18/RPS18 monoclonal antibody | Bovine |
| GM-Tg-equg-INN060-Ab-1/ GM-Tg-equg-INN060-Ab-2 | Anti-Equine 40S ribosomal protein S18/RPS18 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-INN060-Ab-1/ GM-Tg-hg-INN060-Ab-2; GM-Tg-rg-INN060-Ab-1/ GM-Tg-rg-INN060-Ab-2; GM-Tg-mg-INN060-Ab-1/ GM-Tg-mg-INN060-Ab-2; GM-Tg-cynog-INN060-Ab-1/ GM-Tg-cynog-INN060-Ab-2; GM-Tg-felg-INN060-Ab-1/ GM-Tg-felg-INN060-Ab-2; GM-Tg-cang-INN060-Ab-1/ GM-Tg-cang-INN060-Ab-2; GM-Tg-bovg-INN060-Ab-1/ GM-Tg-bovg-INN060-Ab-2; GM-Tg-equg-INN060-Ab-1/ GM-Tg-equg-INN060-Ab-2 |
| Products Name | Anti-40S ribosomal protein S18/RPS18 monoclonal antibody |
| Format | mab |
| Target Name | 40S ribosomal protein S18 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-40S ribosomal protein S18 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-INN-805 | Pre-Made Dorlimomab Aritox Biosimilar, Whole Mab Adc: Anti-40S Ribosomal Protein S18 therapeutic antibody |
| Target Antigen | GM-Tg-g-INN060-Ag-1 | Recombinant multi-species RS18/ 40S ribosomal protein S18/ RPS18 protein |
| ORF Viral Vector | pGMLP000840 | human RPS18 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000840 | human RPS18 Lentivirus particle |
| ORF Viral Vector | pGMLPm000278 | mouse Rps18 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000278 | mouse Rps18 Lentivirus particle |
Target information
| Target ID | GM-INN060 |
| Target Name | 40S ribosomal protein S18 |
| Gene ID | 6222,20084,294282,706414,403685,111560447,326602,100052654 |
| Gene Symbol and Synonyms | D6S218E,H-2Ke3,H2-Ke3,HKE3,KE-3,KE3,RPS18,S18,uS13 |
| Uniprot Accession | P62269,P62270,P62271,Q5TJE9,Q3T0R1 |
| Uniprot Entry Name | RS18_HUMAN,RS18_MOUSE,RS18_RAT,RS18_CANLF,RS18_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, INN Index |
| Disease | N/A |
| Gene Ensembl | ENSG00000231500 |
| Target Classification | N/A |
The target: 40S ribosomal protein S18, gene name: RPS18, also named as D6S218E, HKE3, KE-3, KE3, S18. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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