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Anti-RPGR monoclonal antibody
Pre-made anti-RPGR monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPGR/RPGR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0032-Ab-1/ GM-Tg-hg-IP0032-Ab-2 | Anti-Human RPGR monoclonal antibody | Human |
| GM-Tg-rg-IP0032-Ab-1/ GM-Tg-rg-IP0032-Ab-2 | Anti-Rat RPGR monoclonal antibody | Rat |
| GM-Tg-mg-IP0032-Ab-1/ GM-Tg-mg-IP0032-Ab-2 | Anti-Mouse RPGR monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0032-Ab-1/ GM-Tg-cynog-IP0032-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPGR monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0032-Ab-1/ GM-Tg-felg-IP0032-Ab-2 | Anti-Feline RPGR monoclonal antibody | Feline |
| GM-Tg-cang-IP0032-Ab-1/ GM-Tg-cang-IP0032-Ab-2 | Anti-Canine RPGR monoclonal antibody | Canine |
| GM-Tg-bovg-IP0032-Ab-1/ GM-Tg-bovg-IP0032-Ab-2 | Anti-Bovine RPGR monoclonal antibody | Bovine |
| GM-Tg-equg-IP0032-Ab-1/ GM-Tg-equg-IP0032-Ab-2 | Anti-Equine RPGR monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0032-Ab-1/ GM-Tg-hg-IP0032-Ab-2; GM-Tg-rg-IP0032-Ab-1/ GM-Tg-rg-IP0032-Ab-2; GM-Tg-mg-IP0032-Ab-1/ GM-Tg-mg-IP0032-Ab-2; GM-Tg-cynog-IP0032-Ab-1/ GM-Tg-cynog-IP0032-Ab-2; GM-Tg-felg-IP0032-Ab-1/ GM-Tg-felg-IP0032-Ab-2; GM-Tg-cang-IP0032-Ab-1/ GM-Tg-cang-IP0032-Ab-2; GM-Tg-bovg-IP0032-Ab-1/ GM-Tg-bovg-IP0032-Ab-2; GM-Tg-equg-IP0032-Ab-1/ GM-Tg-equg-IP0032-Ab-2 |
| Products Name | Anti-RPGR monoclonal antibody |
| Format | mab |
| Target Name | RPGR |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPGR monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0032-Ag-1 | Recombinant multi-species RPGR/ COD1/ CORDX1 protein |
| ORF Viral Vector | pGMLPm003633 | mouse Rpgr Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003633 | mouse Rpgr Lentivirus particle |
Target information
| Target ID | GM-IP0032 |
| Target Name | RPGR |
| Gene ID | 6103,19893,367733,714316,403726,101087559,513263,100055608 |
| Gene Symbol and Synonyms | COD1,CORDX1,CRD,orf15,PCDX,Rd9,RP15,RP3,Rp3h,RPGR,XLRP3 |
| Uniprot Accession | Q92834,Q9N1T2 |
| Uniprot Entry Name | RPGR_HUMAN,RPGR_CANLF |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000156313 |
| Target Classification | N/A |
The target: RPGR, gene name: RPGR, also named as COD1, CORDX1, CRD, PCDX, RP15, RP3, XLRP3, orf15. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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