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Anti-VDAC3 monoclonal antibody
Pre-made anti-VDAC3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to VDAC3/VDAC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0073-Ab-1/ GM-Tg-hg-IP0073-Ab-2 | Anti-Human VDAC3 monoclonal antibody | Human |
| GM-Tg-rg-IP0073-Ab-1/ GM-Tg-rg-IP0073-Ab-2 | Anti-Rat VDAC3 monoclonal antibody | Rat |
| GM-Tg-mg-IP0073-Ab-1/ GM-Tg-mg-IP0073-Ab-2 | Anti-Mouse VDAC3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0073-Ab-1/ GM-Tg-cynog-IP0073-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VDAC3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0073-Ab-1/ GM-Tg-felg-IP0073-Ab-2 | Anti-Feline VDAC3 monoclonal antibody | Feline |
| GM-Tg-cang-IP0073-Ab-1/ GM-Tg-cang-IP0073-Ab-2 | Anti-Canine VDAC3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0073-Ab-1/ GM-Tg-bovg-IP0073-Ab-2 | Anti-Bovine VDAC3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0073-Ab-1/ GM-Tg-equg-IP0073-Ab-2 | Anti-Equine VDAC3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0073-Ab-1/ GM-Tg-hg-IP0073-Ab-2; GM-Tg-rg-IP0073-Ab-1/ GM-Tg-rg-IP0073-Ab-2; GM-Tg-mg-IP0073-Ab-1/ GM-Tg-mg-IP0073-Ab-2; GM-Tg-cynog-IP0073-Ab-1/ GM-Tg-cynog-IP0073-Ab-2; GM-Tg-felg-IP0073-Ab-1/ GM-Tg-felg-IP0073-Ab-2; GM-Tg-cang-IP0073-Ab-1/ GM-Tg-cang-IP0073-Ab-2; GM-Tg-bovg-IP0073-Ab-1/ GM-Tg-bovg-IP0073-Ab-2; GM-Tg-equg-IP0073-Ab-1/ GM-Tg-equg-IP0073-Ab-2 |
| Products Name | Anti-VDAC3 monoclonal antibody |
| Format | mab |
| Target Name | VDAC3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-VDAC3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0073-Ag-1 | Recombinant multi-species VDAC3/ HD-VDAC3/ VDAC-3 protein |
| ORF Viral Vector | vGMAD000188 | human VDAC3 Adenovirus particle |
| ORF Viral Vector | pGMLP003366 | human VDAC3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003366 | human VDAC3 Lentivirus particle |
| ORF Viral Vector | pGMAD000188 | human VDAC3 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000867 | mouse Vdac3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000867 | mouse Vdac3 Lentivirus particle |
Target information
| Target ID | GM-IP0073 |
| Target Name | VDAC3 |
| Gene ID | 7419,22335,83532,705116,606963,101099117,282716,100050036 |
| Gene Symbol and Synonyms | HD-VDAC3,VDAC-3,VDAC1P5,VDAC3,VDAC5P |
| Uniprot Accession | Q9Y277,Q9R1Z0,Q9MZ13 |
| Uniprot Entry Name | VDAC3_HUMAN,VDAC3_RAT,VDAC3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000078668 |
| Target Classification | N/A |
The target: VDAC3, gene name: VDAC3, also named as HD-VDAC3, VDAC-3. This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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