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Anti-™PRSS15 monoclonal antibody
Pre-made anti-™PRSS15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ™PRSS15/™PRSS15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0123-Ab-1/ GM-Tg-hg-IP0123-Ab-2 | Anti-Human ™PRSS15 monoclonal antibody | Human |
| GM-Tg-rg-IP0123-Ab-1/ GM-Tg-rg-IP0123-Ab-2 | Anti-Rat ™PRSS15 monoclonal antibody | Rat |
| GM-Tg-mg-IP0123-Ab-1/ GM-Tg-mg-IP0123-Ab-2 | Anti-Mouse ™PRSS15 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0123-Ab-1/ GM-Tg-cynog-IP0123-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ™PRSS15 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0123-Ab-1/ GM-Tg-felg-IP0123-Ab-2 | Anti-Feline ™PRSS15 monoclonal antibody | Feline |
| GM-Tg-cang-IP0123-Ab-1/ GM-Tg-cang-IP0123-Ab-2 | Anti-Canine ™PRSS15 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0123-Ab-1/ GM-Tg-bovg-IP0123-Ab-2 | Anti-Bovine ™PRSS15 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0123-Ab-1/ GM-Tg-equg-IP0123-Ab-2 | Anti-Equine ™PRSS15 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0123-Ab-1/ GM-Tg-hg-IP0123-Ab-2; GM-Tg-rg-IP0123-Ab-1/ GM-Tg-rg-IP0123-Ab-2; GM-Tg-mg-IP0123-Ab-1/ GM-Tg-mg-IP0123-Ab-2; GM-Tg-cynog-IP0123-Ab-1/ GM-Tg-cynog-IP0123-Ab-2; GM-Tg-felg-IP0123-Ab-1/ GM-Tg-felg-IP0123-Ab-2; GM-Tg-cang-IP0123-Ab-1/ GM-Tg-cang-IP0123-Ab-2; GM-Tg-bovg-IP0123-Ab-1/ GM-Tg-bovg-IP0123-Ab-2; GM-Tg-equg-IP0123-Ab-1/ GM-Tg-equg-IP0123-Ab-2 |
| Products Name | Anti-™PRSS15 monoclonal antibody |
| Format | mab |
| Target Name | ™PRSS15 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-™PRSS15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0123-Ag-1 | Recombinant multi-species ENTK/ ™PRSS15/ PRSS7 protein |
Target information
| Target ID | GM-IP0123 |
| Target Name | ™PRSS15 |
| Gene ID | 5651,19146,288291,100423099,487700,101088868,282009,100067591 |
| Gene Symbol and Synonyms | ENTK,PRSS7,™PRSS15 |
| Uniprot Accession | P98073,P98072 |
| Uniprot Entry Name | ENTK_HUMAN,ENTK_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000154646 |
| Target Classification | N/A |
The target: ™PRSS15, gene name: ™PRSS15, also named as ENTK, PRSS7. This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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