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Anti-S™N1 monoclonal antibody
Pre-made anti-S™N1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to S™N1/S™N1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0228-Ab-1/ GM-Tg-hg-IP0228-Ab-2 | Anti-Human S™N1 monoclonal antibody | Human |
| GM-Tg-rg-IP0228-Ab-1/ GM-Tg-rg-IP0228-Ab-2 | Anti-Rat S™N1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0228-Ab-1/ GM-Tg-mg-IP0228-Ab-2 | Anti-Mouse S™N1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0228-Ab-1/ GM-Tg-cynog-IP0228-Ab-2 | Anti-Cynomolgus/ Rhesus macaque S™N1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0228-Ab-1/ GM-Tg-felg-IP0228-Ab-2 | Anti-Feline S™N1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0228-Ab-1/ GM-Tg-cang-IP0228-Ab-2 | Anti-Canine S™N1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0228-Ab-1/ GM-Tg-bovg-IP0228-Ab-2 | Anti-Bovine S™N1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0228-Ab-1/ GM-Tg-equg-IP0228-Ab-2 | Anti-Equine S™N1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0228-Ab-1/ GM-Tg-hg-IP0228-Ab-2; GM-Tg-rg-IP0228-Ab-1/ GM-Tg-rg-IP0228-Ab-2; GM-Tg-mg-IP0228-Ab-1/ GM-Tg-mg-IP0228-Ab-2; GM-Tg-cynog-IP0228-Ab-1/ GM-Tg-cynog-IP0228-Ab-2; GM-Tg-felg-IP0228-Ab-1/ GM-Tg-felg-IP0228-Ab-2; GM-Tg-cang-IP0228-Ab-1/ GM-Tg-cang-IP0228-Ab-2; GM-Tg-bovg-IP0228-Ab-1/ GM-Tg-bovg-IP0228-Ab-2; GM-Tg-equg-IP0228-Ab-1/ GM-Tg-equg-IP0228-Ab-2 |
| Products Name | Anti-S™N1 monoclonal antibody |
| Format | mab |
| Target Name | S™N1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-S™N1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0228-Ag-1 | Recombinant multi-species S™N1/ C1orf215/ LAP18 protein |
| ORF Viral Vector | pGMLV000379 | human S™N1 Lentivirus plasmid |
| ORF Viral Vector | vGMAD000071 | human S™N1 Adenovirus particle |
| ORF Viral Vector | vGMLV000481 | human S™N1 Lentivirus particle |
| ORF Viral Vector | vGMLV000379 | human S™N1 Lentivirus particle |
| ORF Viral Vector | pGMLV000481 | human S™N1 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000293 | Human S™N1 Adenovirus particle |
| ORF Viral Vector | pGMAP000293 | Human S™N1 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000071 | human S™N1 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000212 | mouse Stmn1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000212 | mouse Stmn1 Lentivirus particle |
Target information
| Target ID | GM-IP0228 |
| Target Name | S™N1 |
| Gene ID | 3925,16765,29332,719733,478175,101082582,616317,100057411 |
| Gene Symbol and Synonyms | 19k,C1orf215,Lag,LAP18,OP18,P18,P19,Pig,PP17,Pp18,PP19,PR22,prosolin,SMN,S™N1 |
| Uniprot Accession | P16949,P13668,Q3T0C7 |
| Uniprot Entry Name | S™N1_HUMAN,S™N1_RAT,S™N1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000117632 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: S™N1, gene name: S™N1, also named as C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN. This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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