- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-BSCL2 monoclonal antibody
Pre-made anti-BSCL2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to BSCL2/BSCL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0432-Ab-1/ GM-Tg-hg-IP0432-Ab-2 | Anti-Human BSCL2 monoclonal antibody | Human |
| GM-Tg-rg-IP0432-Ab-1/ GM-Tg-rg-IP0432-Ab-2 | Anti-Rat BSCL2 monoclonal antibody | Rat |
| GM-Tg-mg-IP0432-Ab-1/ GM-Tg-mg-IP0432-Ab-2 | Anti-Mouse BSCL2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0432-Ab-1/ GM-Tg-cynog-IP0432-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BSCL2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0432-Ab-1/ GM-Tg-felg-IP0432-Ab-2 | Anti-Feline BSCL2 monoclonal antibody | Feline |
| GM-Tg-cang-IP0432-Ab-1/ GM-Tg-cang-IP0432-Ab-2 | Anti-Canine BSCL2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0432-Ab-1/ GM-Tg-bovg-IP0432-Ab-2 | Anti-Bovine BSCL2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0432-Ab-1/ GM-Tg-equg-IP0432-Ab-2 | Anti-Equine BSCL2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0432-Ab-1/ GM-Tg-hg-IP0432-Ab-2; GM-Tg-rg-IP0432-Ab-1/ GM-Tg-rg-IP0432-Ab-2; GM-Tg-mg-IP0432-Ab-1/ GM-Tg-mg-IP0432-Ab-2; GM-Tg-cynog-IP0432-Ab-1/ GM-Tg-cynog-IP0432-Ab-2; GM-Tg-felg-IP0432-Ab-1/ GM-Tg-felg-IP0432-Ab-2; GM-Tg-cang-IP0432-Ab-1/ GM-Tg-cang-IP0432-Ab-2; GM-Tg-bovg-IP0432-Ab-1/ GM-Tg-bovg-IP0432-Ab-2; GM-Tg-equg-IP0432-Ab-1/ GM-Tg-equg-IP0432-Ab-2 |
| Products Name | Anti-BSCL2 monoclonal antibody |
| Format | mab |
| Target Name | BSCL2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-BSCL2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0432-Ag-1 | Recombinant multi-species BSCL2/ GNG3LG/ HMN5 protein |
| ORF Viral Vector | pGMAAV000012 | human BSCL2 AAV plasmid |
| ORF Viral Vector | vGMLP003362 | human BSCL2 Lentivirus particle |
| ORF Viral Vector | pGMLP003362 | human BSCL2 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000012 | human BSCL2 AAV particle |
| ORF Viral Vector | pGMLPm003839 | mouse Bscl2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003839 | mouse Bscl2 Lentivirus particle |
Target information
| Target ID | GM-IP0432 |
| Target Name | BSCL2 |
| Gene ID | 26580,14705,361722,100428843,476054,101091148,513558,100063764 |
| Gene Symbol and Synonyms | 2900097C17Rik,BSCL2,GNG3LG,HMN5,HMN5C,PELD,SPG17 |
| Uniprot Accession | Q96G97,Q5FVJ6,Q5E9P6 |
| Uniprot Entry Name | BSCL2_HUMAN,BSCL2_RAT,BSCL2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000168000 |
| Target Classification | N/A |
The target: BSCL2, gene name: BSCL2, also named as GNG3LG, HMN5, PELD, SPG17. This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
