Anti-CERS2 monoclonal antibody

Pre-made anti-CERS2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CERS2/CERS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0534-Ab-1/ GM-Tg-hg-IP0534-Ab-2Anti-Human CERS2 monoclonal antibodyHuman
GM-Tg-rg-IP0534-Ab-1/ GM-Tg-rg-IP0534-Ab-2Anti-Rat CERS2 monoclonal antibodyRat
GM-Tg-mg-IP0534-Ab-1/ GM-Tg-mg-IP0534-Ab-2Anti-Mouse CERS2 monoclonal antibodyMouse
GM-Tg-cynog-IP0534-Ab-1/ GM-Tg-cynog-IP0534-Ab-2Anti-Cynomolgus/ Rhesus macaque CERS2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0534-Ab-1/ GM-Tg-felg-IP0534-Ab-2Anti-Feline CERS2 monoclonal antibodyFeline
GM-Tg-cang-IP0534-Ab-1/ GM-Tg-cang-IP0534-Ab-2Anti-Canine CERS2 monoclonal antibodyCanine
GM-Tg-bovg-IP0534-Ab-1/ GM-Tg-bovg-IP0534-Ab-2Anti-Bovine CERS2 monoclonal antibodyBovine
GM-Tg-equg-IP0534-Ab-1/ GM-Tg-equg-IP0534-Ab-2Anti-Equine CERS2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0534-Ab-1/ GM-Tg-hg-IP0534-Ab-2; GM-Tg-rg-IP0534-Ab-1/ GM-Tg-rg-IP0534-Ab-2;
GM-Tg-mg-IP0534-Ab-1/ GM-Tg-mg-IP0534-Ab-2; GM-Tg-cynog-IP0534-Ab-1/ GM-Tg-cynog-IP0534-Ab-2;
GM-Tg-felg-IP0534-Ab-1/ GM-Tg-felg-IP0534-Ab-2; GM-Tg-cang-IP0534-Ab-1/ GM-Tg-cang-IP0534-Ab-2;
GM-Tg-bovg-IP0534-Ab-1/ GM-Tg-bovg-IP0534-Ab-2; GM-Tg-equg-IP0534-Ab-1/ GM-Tg-equg-IP0534-Ab-2
Products NameAnti-CERS2 monoclonal antibody
Formatmab
Target NameCERS2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CERS2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0534-Ag-1Recombinant multi-species CERS2/ L3/ LASS2 protein
    ORF Viral VectorpGMLP001470human CERS2 Lentivirus plasmid
    ORF Viral VectorvGMLP001470human CERS2 Lentivirus particle
    ORF Viral VectorpGMAD000344mouse Cers2 Adenovirus plasmid
    ORF Viral VectorpGMAAV000212house mouse Cers2 AAV plasmid
    ORF Viral VectorvGMAD000344mouse Cers2 Adenovirus particle
    ORF Viral VectorvGMAAV000212house mouse Cers2 AAV particle


    Target information

    Target IDGM-IP0534
    Target NameCERS2
    Gene ID29956,76893,310667,716180,483187,101094362,539223,100055037
    Gene Symbol and Synonyms0610013I17Rik,CERS2,L3,LASS2,SP260,™SG1,TRH3
    Uniprot AccessionQ96G23,Q3ZBF8
    Uniprot Entry NameCERS2_HUMAN,CERS2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143418
    Target ClassificationN/A

    The target: CERS2, gene name: CERS2, also named as L3, LASS2, SP260, ™SG1. This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.