Anti-CERS4 monoclonal antibody

Pre-made anti-CERS4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CERS4/CERS4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0536-Ab-1/ GM-Tg-hg-IP0536-Ab-2Anti-Human CERS4 monoclonal antibodyHuman
GM-Tg-rg-IP0536-Ab-1/ GM-Tg-rg-IP0536-Ab-2Anti-Rat CERS4 monoclonal antibodyRat
GM-Tg-mg-IP0536-Ab-1/ GM-Tg-mg-IP0536-Ab-2Anti-Mouse CERS4 monoclonal antibodyMouse
GM-Tg-cynog-IP0536-Ab-1/ GM-Tg-cynog-IP0536-Ab-2Anti-Cynomolgus/ Rhesus macaque CERS4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0536-Ab-1/ GM-Tg-felg-IP0536-Ab-2Anti-Feline CERS4 monoclonal antibodyFeline
GM-Tg-cang-IP0536-Ab-1/ GM-Tg-cang-IP0536-Ab-2Anti-Canine CERS4 monoclonal antibodyCanine
GM-Tg-bovg-IP0536-Ab-1/ GM-Tg-bovg-IP0536-Ab-2Anti-Bovine CERS4 monoclonal antibodyBovine
GM-Tg-equg-IP0536-Ab-1/ GM-Tg-equg-IP0536-Ab-2Anti-Equine CERS4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0536-Ab-1/ GM-Tg-hg-IP0536-Ab-2; GM-Tg-rg-IP0536-Ab-1/ GM-Tg-rg-IP0536-Ab-2;
GM-Tg-mg-IP0536-Ab-1/ GM-Tg-mg-IP0536-Ab-2; GM-Tg-cynog-IP0536-Ab-1/ GM-Tg-cynog-IP0536-Ab-2;
GM-Tg-felg-IP0536-Ab-1/ GM-Tg-felg-IP0536-Ab-2; GM-Tg-cang-IP0536-Ab-1/ GM-Tg-cang-IP0536-Ab-2;
GM-Tg-bovg-IP0536-Ab-1/ GM-Tg-bovg-IP0536-Ab-2; GM-Tg-equg-IP0536-Ab-1/ GM-Tg-equg-IP0536-Ab-2
Products NameAnti-CERS4 monoclonal antibody
Formatmab
Target NameCERS4
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CERS4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0536-Ag-1Recombinant multi-species CERS4/ LASS4/ Trh1 protein


    Target information

    Target IDGM-IP0536
    Target NameCERS4
    Gene ID79603,67260,304208,706728,485008,101093918,505233,100066949
    Gene Symbol and Synonyms2900019C14Rik,CERS4,LASS4,Trh1
    Uniprot AccessionQ9HA82,Q5E9R6
    Uniprot Entry NameCERS4_HUMAN,CERS4_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000090661
    Target ClassificationN/A

    The target: CERS4, gene name: CERS4, also named as LASS4, Trh1. Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.