- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CHRNB1 monoclonal antibody
Pre-made anti-CHRNB1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CHRNB1/CHRNB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0545-Ab-1/ GM-Tg-hg-IP0545-Ab-2 | Anti-Human CHRNB1 monoclonal antibody | Human |
| GM-Tg-rg-IP0545-Ab-1/ GM-Tg-rg-IP0545-Ab-2 | Anti-Rat CHRNB1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0545-Ab-1/ GM-Tg-mg-IP0545-Ab-2 | Anti-Mouse CHRNB1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0545-Ab-1/ GM-Tg-cynog-IP0545-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CHRNB1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0545-Ab-1/ GM-Tg-felg-IP0545-Ab-2 | Anti-Feline CHRNB1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0545-Ab-1/ GM-Tg-cang-IP0545-Ab-2 | Anti-Canine CHRNB1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0545-Ab-1/ GM-Tg-bovg-IP0545-Ab-2 | Anti-Bovine CHRNB1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0545-Ab-1/ GM-Tg-equg-IP0545-Ab-2 | Anti-Equine CHRNB1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0545-Ab-1/ GM-Tg-hg-IP0545-Ab-2; GM-Tg-rg-IP0545-Ab-1/ GM-Tg-rg-IP0545-Ab-2; GM-Tg-mg-IP0545-Ab-1/ GM-Tg-mg-IP0545-Ab-2; GM-Tg-cynog-IP0545-Ab-1/ GM-Tg-cynog-IP0545-Ab-2; GM-Tg-felg-IP0545-Ab-1/ GM-Tg-felg-IP0545-Ab-2; GM-Tg-cang-IP0545-Ab-1/ GM-Tg-cang-IP0545-Ab-2; GM-Tg-bovg-IP0545-Ab-1/ GM-Tg-bovg-IP0545-Ab-2; GM-Tg-equg-IP0545-Ab-1/ GM-Tg-equg-IP0545-Ab-2 |
| Products Name | Anti-CHRNB1 monoclonal antibody |
| Format | mab |
| Target Name | CHRNB1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CHRNB1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0545-Ag-1 | Recombinant multi-species ACHB/ CHRNB1/ ACHRB protein |
Target information
| Target ID | GM-IP0545 |
| Target Name | CHRNB1 |
| Gene ID | 1140,11443,24261,715509,489473,101097433,282179,100072990 |
| Gene Symbol and Synonyms | Achr-2,ACHRB,Acrb,CHRNB,CHRNB1,CMS1D,CMS2A,CMS2C,nAChR,RNACRB1,SCCMS |
| Uniprot Accession | P11230,P25109,P04758 |
| Uniprot Entry Name | ACHB_HUMAN,ACHB_RAT,ACHB_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170175 |
| Target Classification | Ion Channel |
The target: CHRNB1, gene name: CHRNB1, also named as ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS. The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
