Anti-CLRN2 monoclonal antibody

Pre-made anti-CLRN2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CLRN2/CLRN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0566-Ab-1/ GM-Tg-hg-IP0566-Ab-2Anti-Human CLRN2 monoclonal antibodyHuman
GM-Tg-rg-IP0566-Ab-1/ GM-Tg-rg-IP0566-Ab-2Anti-Rat CLRN2 monoclonal antibodyRat
GM-Tg-mg-IP0566-Ab-1/ GM-Tg-mg-IP0566-Ab-2Anti-Mouse CLRN2 monoclonal antibodyMouse
GM-Tg-cynog-IP0566-Ab-1/ GM-Tg-cynog-IP0566-Ab-2Anti-Cynomolgus/ Rhesus macaque CLRN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0566-Ab-1/ GM-Tg-felg-IP0566-Ab-2Anti-Feline CLRN2 monoclonal antibodyFeline
GM-Tg-cang-IP0566-Ab-1/ GM-Tg-cang-IP0566-Ab-2Anti-Canine CLRN2 monoclonal antibodyCanine
GM-Tg-bovg-IP0566-Ab-1/ GM-Tg-bovg-IP0566-Ab-2Anti-Bovine CLRN2 monoclonal antibodyBovine
GM-Tg-equg-IP0566-Ab-1/ GM-Tg-equg-IP0566-Ab-2Anti-Equine CLRN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0566-Ab-1/ GM-Tg-hg-IP0566-Ab-2; GM-Tg-rg-IP0566-Ab-1/ GM-Tg-rg-IP0566-Ab-2;
GM-Tg-mg-IP0566-Ab-1/ GM-Tg-mg-IP0566-Ab-2; GM-Tg-cynog-IP0566-Ab-1/ GM-Tg-cynog-IP0566-Ab-2;
GM-Tg-felg-IP0566-Ab-1/ GM-Tg-felg-IP0566-Ab-2; GM-Tg-cang-IP0566-Ab-1/ GM-Tg-cang-IP0566-Ab-2;
GM-Tg-bovg-IP0566-Ab-1/ GM-Tg-bovg-IP0566-Ab-2; GM-Tg-equg-IP0566-Ab-1/ GM-Tg-equg-IP0566-Ab-2
Products NameAnti-CLRN2 monoclonal antibody
Formatmab
Target NameCLRN2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CLRN2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0566-Ag-1Recombinant multi-species CLRN2 protein


    Target information

    Target IDGM-IP0566
    Target NameCLRN2
    Gene ID645104,624224,689515,722858,610779,101086805,617290,100068682
    Gene Symbol and SynonymsCLRN2,DFNB117,EG624224,mpc169H
    Uniprot AccessionA0PK11
    Uniprot Entry NameCLRN2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000249581
    Target ClassificationN/A

    The target: CLRN2, gene name: CLRN2, also named as . This gene belongs to the clarin family of genes. The clarins appear to belong to a large superfamily of small integral membrane glycoproteins with four transmembrane domains. The exact function of this gene is unknown. [provided by RefSeq, Oct 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.