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Anti-CLSTN3 monoclonal antibody
Pre-made anti-CLSTN3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CLSTN3/CLSTN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0569-Ab-1/ GM-Tg-hg-IP0569-Ab-2 | Anti-Human CLSTN3 monoclonal antibody | Human |
| GM-Tg-rg-IP0569-Ab-1/ GM-Tg-rg-IP0569-Ab-2 | Anti-Rat CLSTN3 monoclonal antibody | Rat |
| GM-Tg-mg-IP0569-Ab-1/ GM-Tg-mg-IP0569-Ab-2 | Anti-Mouse CLSTN3 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0569-Ab-1/ GM-Tg-cynog-IP0569-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CLSTN3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0569-Ab-1/ GM-Tg-felg-IP0569-Ab-2 | Anti-Feline CLSTN3 monoclonal antibody | Feline |
| GM-Tg-cang-IP0569-Ab-1/ GM-Tg-cang-IP0569-Ab-2 | Anti-Canine CLSTN3 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0569-Ab-1/ GM-Tg-bovg-IP0569-Ab-2 | Anti-Bovine CLSTN3 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0569-Ab-1/ GM-Tg-equg-IP0569-Ab-2 | Anti-Equine CLSTN3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0569-Ab-1/ GM-Tg-hg-IP0569-Ab-2; GM-Tg-rg-IP0569-Ab-1/ GM-Tg-rg-IP0569-Ab-2; GM-Tg-mg-IP0569-Ab-1/ GM-Tg-mg-IP0569-Ab-2; GM-Tg-cynog-IP0569-Ab-1/ GM-Tg-cynog-IP0569-Ab-2; GM-Tg-felg-IP0569-Ab-1/ GM-Tg-felg-IP0569-Ab-2; GM-Tg-cang-IP0569-Ab-1/ GM-Tg-cang-IP0569-Ab-2; GM-Tg-bovg-IP0569-Ab-1/ GM-Tg-bovg-IP0569-Ab-2; GM-Tg-equg-IP0569-Ab-1/ GM-Tg-equg-IP0569-Ab-2 |
| Products Name | Anti-CLSTN3 monoclonal antibody |
| Format | mab |
| Target Name | CLSTN3 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CLSTN3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0569-Ag-1 | Recombinant multi-species CSTN3/ CLSTN3/ CDHR14 protein |
Target information
| Target ID | GM-IP0569 |
| Target Name | CLSTN3 |
| Gene ID | 9746,232370,171393,715119,486711,101089620,509969,100053124 |
| Gene Symbol and Synonyms | alc-beta,alcbeta,CDHR14,CLSTN3,Clstn3b,Cs3,Cst-3,CSTN3 |
| Uniprot Accession | Q9BQT9,Q8R553,Q0VCN6 |
| Uniprot Entry Name | CSTN3_HUMAN,CSTN3_RAT,CSTN3_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000139182 |
| Target Classification | N/A |
The target: CLSTN3, gene name: CLSTN3, also named as CDHR14, CSTN3, alcbeta. Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within several processes, including chemical synaptic transmission; positive regulation of protein localization to synapse; and synapse assembly. Predicted to be located in postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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