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Anti-CNTNAP1 monoclonal antibody
Pre-made anti-CNTNAP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CNTNAP1/CNTNAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0586-Ab-1/ GM-Tg-hg-IP0586-Ab-2 | Anti-Human CNTNAP1 monoclonal antibody | Human |
| GM-Tg-rg-IP0586-Ab-1/ GM-Tg-rg-IP0586-Ab-2 | Anti-Rat CNTNAP1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0586-Ab-1/ GM-Tg-mg-IP0586-Ab-2 | Anti-Mouse CNTNAP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0586-Ab-1/ GM-Tg-cynog-IP0586-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CNTNAP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0586-Ab-1/ GM-Tg-felg-IP0586-Ab-2 | Anti-Feline CNTNAP1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0586-Ab-1/ GM-Tg-cang-IP0586-Ab-2 | Anti-Canine CNTNAP1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0586-Ab-1/ GM-Tg-bovg-IP0586-Ab-2 | Anti-Bovine CNTNAP1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0586-Ab-1/ GM-Tg-equg-IP0586-Ab-2 | Anti-Equine CNTNAP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0586-Ab-1/ GM-Tg-hg-IP0586-Ab-2; GM-Tg-rg-IP0586-Ab-1/ GM-Tg-rg-IP0586-Ab-2; GM-Tg-mg-IP0586-Ab-1/ GM-Tg-mg-IP0586-Ab-2; GM-Tg-cynog-IP0586-Ab-1/ GM-Tg-cynog-IP0586-Ab-2; GM-Tg-felg-IP0586-Ab-1/ GM-Tg-felg-IP0586-Ab-2; GM-Tg-cang-IP0586-Ab-1/ GM-Tg-cang-IP0586-Ab-2; GM-Tg-bovg-IP0586-Ab-1/ GM-Tg-bovg-IP0586-Ab-2; GM-Tg-equg-IP0586-Ab-1/ GM-Tg-equg-IP0586-Ab-2 |
| Products Name | Anti-CNTNAP1 monoclonal antibody |
| Format | mab |
| Target Name | CNTNAP1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CNTNAP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0586-Ag-1 | Recombinant multi-species CNTP1/ CNTNAP1/ CASPR protein |
Target information
| Target ID | GM-IP0586 |
| Target Name | CNTNAP1 |
| Gene ID | 8506,53321,84008,574229,490960,101099341,540997,100052467 |
| Gene Symbol and Synonyms | CASPR,CHN3,CNTNAP,CNTNAP1,NCP1,NRXN4,P190,shm |
| Uniprot Accession | P78357,P97846 |
| Uniprot Entry Name | CNTP1_HUMAN,CNTP1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000108797 |
| Target Classification | N/A |
The target: CNTNAP1, gene name: CNTNAP1, also named as CASPR, CNTNAP, NRXN4, P190. The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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