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Anti-COX15 monoclonal antibody
Pre-made anti-COX15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to COX15/COX15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0596-Ab-1/ GM-Tg-hg-IP0596-Ab-2 | Anti-Human COX15 monoclonal antibody | Human |
| GM-Tg-rg-IP0596-Ab-1/ GM-Tg-rg-IP0596-Ab-2 | Anti-Rat COX15 monoclonal antibody | Rat |
| GM-Tg-mg-IP0596-Ab-1/ GM-Tg-mg-IP0596-Ab-2 | Anti-Mouse COX15 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0596-Ab-1/ GM-Tg-cynog-IP0596-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COX15 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0596-Ab-1/ GM-Tg-felg-IP0596-Ab-2 | Anti-Feline COX15 monoclonal antibody | Feline |
| GM-Tg-cang-IP0596-Ab-1/ GM-Tg-cang-IP0596-Ab-2 | Anti-Canine COX15 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0596-Ab-1/ GM-Tg-bovg-IP0596-Ab-2 | Anti-Bovine COX15 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0596-Ab-1/ GM-Tg-equg-IP0596-Ab-2 | Anti-Equine COX15 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0596-Ab-1/ GM-Tg-hg-IP0596-Ab-2; GM-Tg-rg-IP0596-Ab-1/ GM-Tg-rg-IP0596-Ab-2; GM-Tg-mg-IP0596-Ab-1/ GM-Tg-mg-IP0596-Ab-2; GM-Tg-cynog-IP0596-Ab-1/ GM-Tg-cynog-IP0596-Ab-2; GM-Tg-felg-IP0596-Ab-1/ GM-Tg-felg-IP0596-Ab-2; GM-Tg-cang-IP0596-Ab-1/ GM-Tg-cang-IP0596-Ab-2; GM-Tg-bovg-IP0596-Ab-1/ GM-Tg-bovg-IP0596-Ab-2; GM-Tg-equg-IP0596-Ab-1/ GM-Tg-equg-IP0596-Ab-2 |
| Products Name | Anti-COX15 monoclonal antibody |
| Format | mab |
| Target Name | COX15 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-COX15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0596-Ag-1 | Recombinant multi-species COX15/ CEMCOX2 protein |
Target information
| Target ID | GM-IP0596 |
| Target Name | COX15 |
| Gene ID | 1355,226139,309391,708964,477792,101085408,517811,100060721 |
| Gene Symbol and Synonyms | 2900026G05Rik,CEMCOX2,COX15,MC4DN6 |
| Uniprot Accession | Q7KZN9,Q08DG6 |
| Uniprot Entry Name | COX15_HUMAN,COX15_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000014919 |
| Target Classification | N/A |
The target: COX15, gene name: COX15, also named as CEMCOX2. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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