- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-COX6C monoclonal antibody
Pre-made anti-COX6C monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to COX6C/COX6C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0602-Ab-1/ GM-Tg-hg-IP0602-Ab-2 | Anti-Human COX6C monoclonal antibody | Human |
| GM-Tg-rg-IP0602-Ab-1/ GM-Tg-rg-IP0602-Ab-2 | Anti-Rat COX6C monoclonal antibody | Rat |
| GM-Tg-mg-IP0602-Ab-1/ GM-Tg-mg-IP0602-Ab-2 | Anti-Mouse COX6C monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0602-Ab-1/ GM-Tg-cynog-IP0602-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COX6C monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0602-Ab-1/ GM-Tg-felg-IP0602-Ab-2 | Anti-Feline COX6C monoclonal antibody | Feline |
| GM-Tg-cang-IP0602-Ab-1/ GM-Tg-cang-IP0602-Ab-2 | Anti-Canine COX6C monoclonal antibody | Canine |
| GM-Tg-bovg-IP0602-Ab-1/ GM-Tg-bovg-IP0602-Ab-2 | Anti-Bovine COX6C monoclonal antibody | Bovine |
| GM-Tg-equg-IP0602-Ab-1/ GM-Tg-equg-IP0602-Ab-2 | Anti-Equine COX6C monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0602-Ab-1/ GM-Tg-hg-IP0602-Ab-2; GM-Tg-rg-IP0602-Ab-1/ GM-Tg-rg-IP0602-Ab-2; GM-Tg-mg-IP0602-Ab-1/ GM-Tg-mg-IP0602-Ab-2; GM-Tg-cynog-IP0602-Ab-1/ GM-Tg-cynog-IP0602-Ab-2; GM-Tg-felg-IP0602-Ab-1/ GM-Tg-felg-IP0602-Ab-2; GM-Tg-cang-IP0602-Ab-1/ GM-Tg-cang-IP0602-Ab-2; GM-Tg-bovg-IP0602-Ab-1/ GM-Tg-bovg-IP0602-Ab-2; GM-Tg-equg-IP0602-Ab-1/ GM-Tg-equg-IP0602-Ab-2 |
| Products Name | Anti-COX6C monoclonal antibody |
| Format | mab |
| Target Name | COX6C |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-COX6C monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0602-Ag-1 | Recombinant multi-species COX6C protein |
Target information
| Target ID | GM-IP0602 |
| Target Name | COX6C |
| Gene ID | 1345,12864,54322,100428417,101096876,614700,100055813 |
| Gene Symbol and Synonyms | COVIc,COX-VIc,COX6C,Cox6c2,LOC100055813,LOC101096876 |
| Uniprot Accession | P09669,P11951 |
| Uniprot Entry Name | COX6C_HUMAN,CX6C2_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000164919 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: COX6C, gene name: COX6C, also named as . Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
