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Anti-CPT1A monoclonal antibody
Pre-made anti-CPT1A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CPT1A/CPT1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0608-Ab-1/ GM-Tg-hg-IP0608-Ab-2 | Anti-Human CPT1A monoclonal antibody | Human |
| GM-Tg-rg-IP0608-Ab-1/ GM-Tg-rg-IP0608-Ab-2 | Anti-Rat CPT1A monoclonal antibody | Rat |
| GM-Tg-mg-IP0608-Ab-1/ GM-Tg-mg-IP0608-Ab-2 | Anti-Mouse CPT1A monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0608-Ab-1/ GM-Tg-cynog-IP0608-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CPT1A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0608-Ab-1/ GM-Tg-felg-IP0608-Ab-2 | Anti-Feline CPT1A monoclonal antibody | Feline |
| GM-Tg-cang-IP0608-Ab-1/ GM-Tg-cang-IP0608-Ab-2 | Anti-Canine CPT1A monoclonal antibody | Canine |
| GM-Tg-bovg-IP0608-Ab-1/ GM-Tg-bovg-IP0608-Ab-2 | Anti-Bovine CPT1A monoclonal antibody | Bovine |
| GM-Tg-equg-IP0608-Ab-1/ GM-Tg-equg-IP0608-Ab-2 | Anti-Equine CPT1A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0608-Ab-1/ GM-Tg-hg-IP0608-Ab-2; GM-Tg-rg-IP0608-Ab-1/ GM-Tg-rg-IP0608-Ab-2; GM-Tg-mg-IP0608-Ab-1/ GM-Tg-mg-IP0608-Ab-2; GM-Tg-cynog-IP0608-Ab-1/ GM-Tg-cynog-IP0608-Ab-2; GM-Tg-felg-IP0608-Ab-1/ GM-Tg-felg-IP0608-Ab-2; GM-Tg-cang-IP0608-Ab-1/ GM-Tg-cang-IP0608-Ab-2; GM-Tg-bovg-IP0608-Ab-1/ GM-Tg-bovg-IP0608-Ab-2; GM-Tg-equg-IP0608-Ab-1/ GM-Tg-equg-IP0608-Ab-2 |
| Products Name | Anti-CPT1A monoclonal antibody |
| Format | mab |
| Target Name | CPT1A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CPT1A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0608-Ag-1 | Recombinant multi-species CPT1A/ CPT1/ CPT1-L protein |
| ORF Viral Vector | vGMLP001928 | human CPT1A Lentivirus particle |
| ORF Viral Vector | pGMLP001928 | human CPT1A Lentivirus plasmid |
Target information
| Target ID | GM-IP0608 |
| Target Name | CPT1A |
| Gene ID | 1374,12894,25757,709837,403583,101096105,506812,100009716 |
| Gene Symbol and Synonyms | C730027G07,CPT-Ia,CPT1,CPT1-L,CPT1A,CPTI,L-CPT1 |
| Uniprot Accession | P50416,P32198,Q68Y62 |
| Uniprot Entry Name | CPT1A_HUMAN,CPT1A_RAT,CPT1A_HORSE |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000110090 |
| Target Classification | N/A |
The target: CPT1A, gene name: CPT1A, also named as CPT1, CPT1-L, L-CPT1. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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