Anti-CUX1 monoclonal antibody

Pre-made anti-CUX1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CUX1/CUX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0629-Ab-1/ GM-Tg-hg-IP0629-Ab-2Anti-Human CUX1 monoclonal antibodyHuman
GM-Tg-rg-IP0629-Ab-1/ GM-Tg-rg-IP0629-Ab-2Anti-Rat CUX1 monoclonal antibodyRat
GM-Tg-mg-IP0629-Ab-1/ GM-Tg-mg-IP0629-Ab-2Anti-Mouse CUX1 monoclonal antibodyMouse
GM-Tg-cynog-IP0629-Ab-1/ GM-Tg-cynog-IP0629-Ab-2Anti-Cynomolgus/ Rhesus macaque CUX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0629-Ab-1/ GM-Tg-felg-IP0629-Ab-2Anti-Feline CUX1 monoclonal antibodyFeline
GM-Tg-cang-IP0629-Ab-1/ GM-Tg-cang-IP0629-Ab-2Anti-Canine CUX1 monoclonal antibodyCanine
GM-Tg-bovg-IP0629-Ab-1/ GM-Tg-bovg-IP0629-Ab-2Anti-Bovine CUX1 monoclonal antibodyBovine
GM-Tg-equg-IP0629-Ab-1/ GM-Tg-equg-IP0629-Ab-2Anti-Equine CUX1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0629-Ab-1/ GM-Tg-hg-IP0629-Ab-2; GM-Tg-rg-IP0629-Ab-1/ GM-Tg-rg-IP0629-Ab-2;
GM-Tg-mg-IP0629-Ab-1/ GM-Tg-mg-IP0629-Ab-2; GM-Tg-cynog-IP0629-Ab-1/ GM-Tg-cynog-IP0629-Ab-2;
GM-Tg-felg-IP0629-Ab-1/ GM-Tg-felg-IP0629-Ab-2; GM-Tg-cang-IP0629-Ab-1/ GM-Tg-cang-IP0629-Ab-2;
GM-Tg-bovg-IP0629-Ab-1/ GM-Tg-bovg-IP0629-Ab-2; GM-Tg-equg-IP0629-Ab-1/ GM-Tg-equg-IP0629-Ab-2
Products NameAnti-CUX1 monoclonal antibody
Formatmab
Target NameCUX1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CUX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0629-Ag-1Recombinant multi-species CUX1/ CASP/ CUX1 protein


    Target information

    Target IDGM-IP0629
    Target NameCUX1
    Gene ID1523,13047,116639,574390,489821,101082615,523683,100060510
    Gene Symbol and SynonymsCASP,CDP,CDP/Cut,CDP1,CDP2,Clox,Clox-1,COY1,CUTL1,CUX,Cux-1,Cux/CDP,CUX1,GDDI,GOLIM6,Nbla10317,p100,p110,p200,p75
    Uniprot AccessionP39880, Q13948,P53565,P39881
    Uniprot Entry NameCASP_HUMAN,CUX1_RAT,CUX1_CANLF
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000257923
    Target ClassificationN/A

    The target: CUX1, gene name: CUX1, also named as CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75. The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.