- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CYP20A1 monoclonal antibody
Pre-made anti-CYP20A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CYP20A1/CYP20A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0644-Ab-1/ GM-Tg-hg-IP0644-Ab-2 | Anti-Human CYP20A1 monoclonal antibody | Human |
| GM-Tg-rg-IP0644-Ab-1/ GM-Tg-rg-IP0644-Ab-2 | Anti-Rat CYP20A1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0644-Ab-1/ GM-Tg-mg-IP0644-Ab-2 | Anti-Mouse CYP20A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0644-Ab-1/ GM-Tg-cynog-IP0644-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CYP20A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0644-Ab-1/ GM-Tg-felg-IP0644-Ab-2 | Anti-Feline CYP20A1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0644-Ab-1/ GM-Tg-cang-IP0644-Ab-2 | Anti-Canine CYP20A1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0644-Ab-1/ GM-Tg-bovg-IP0644-Ab-2 | Anti-Bovine CYP20A1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0644-Ab-1/ GM-Tg-equg-IP0644-Ab-2 | Anti-Equine CYP20A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0644-Ab-1/ GM-Tg-hg-IP0644-Ab-2; GM-Tg-rg-IP0644-Ab-1/ GM-Tg-rg-IP0644-Ab-2; GM-Tg-mg-IP0644-Ab-1/ GM-Tg-mg-IP0644-Ab-2; GM-Tg-cynog-IP0644-Ab-1/ GM-Tg-cynog-IP0644-Ab-2; GM-Tg-felg-IP0644-Ab-1/ GM-Tg-felg-IP0644-Ab-2; GM-Tg-cang-IP0644-Ab-1/ GM-Tg-cang-IP0644-Ab-2; GM-Tg-bovg-IP0644-Ab-1/ GM-Tg-bovg-IP0644-Ab-2; GM-Tg-equg-IP0644-Ab-1/ GM-Tg-equg-IP0644-Ab-2 |
| Products Name | Anti-CYP20A1 monoclonal antibody |
| Format | mab |
| Target Name | CYP20A1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CYP20A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0644-Ag-1 | Recombinant multi-species CP20A/ CYP20A1/ CYP-M protein |
Target information
| Target ID | GM-IP0644 |
| Target Name | CYP20A1 |
| Gene ID | 57404,77951,316435,715257,100686469,101088261,532945,100067617 |
| Gene Symbol and Synonyms | A930011N14Rik,CYP-M,CYP20A1,Cypm |
| Uniprot Accession | Q6UW02,Q6P7D4,Q5E980 |
| Uniprot Entry Name | CP20A_HUMAN,CP20A_RAT,CP20A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000119004 |
| Target Classification | N/A |
The target: CYP20A1, gene name: CYP20A1, also named as CYP-M. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
