Anti-CYP2U1 monoclonal antibody

Pre-made anti-CYP2U1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CYP2U1/CYP2U1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0647-Ab-1/ GM-Tg-hg-IP0647-Ab-2Anti-Human CYP2U1 monoclonal antibodyHuman
GM-Tg-rg-IP0647-Ab-1/ GM-Tg-rg-IP0647-Ab-2Anti-Rat CYP2U1 monoclonal antibodyRat
GM-Tg-mg-IP0647-Ab-1/ GM-Tg-mg-IP0647-Ab-2Anti-Mouse CYP2U1 monoclonal antibodyMouse
GM-Tg-cynog-IP0647-Ab-1/ GM-Tg-cynog-IP0647-Ab-2Anti-Cynomolgus/ Rhesus macaque CYP2U1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0647-Ab-1/ GM-Tg-felg-IP0647-Ab-2Anti-Feline CYP2U1 monoclonal antibodyFeline
GM-Tg-cang-IP0647-Ab-1/ GM-Tg-cang-IP0647-Ab-2Anti-Canine CYP2U1 monoclonal antibodyCanine
GM-Tg-bovg-IP0647-Ab-1/ GM-Tg-bovg-IP0647-Ab-2Anti-Bovine CYP2U1 monoclonal antibodyBovine
GM-Tg-equg-IP0647-Ab-1/ GM-Tg-equg-IP0647-Ab-2Anti-Equine CYP2U1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0647-Ab-1/ GM-Tg-hg-IP0647-Ab-2; GM-Tg-rg-IP0647-Ab-1/ GM-Tg-rg-IP0647-Ab-2;
GM-Tg-mg-IP0647-Ab-1/ GM-Tg-mg-IP0647-Ab-2; GM-Tg-cynog-IP0647-Ab-1/ GM-Tg-cynog-IP0647-Ab-2;
GM-Tg-felg-IP0647-Ab-1/ GM-Tg-felg-IP0647-Ab-2; GM-Tg-cang-IP0647-Ab-1/ GM-Tg-cang-IP0647-Ab-2;
GM-Tg-bovg-IP0647-Ab-1/ GM-Tg-bovg-IP0647-Ab-2; GM-Tg-equg-IP0647-Ab-1/ GM-Tg-equg-IP0647-Ab-2
Products NameAnti-CYP2U1 monoclonal antibody
Formatmab
Target NameCYP2U1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CYP2U1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0647-Ag-1Recombinant multi-species CP2U1/ CYP2U1/ P450TEC protein


    Target information

    Target IDGM-IP0647
    Target NameCYP2U1
    Gene ID113612,71519,310848,696076,100685915,101089856,535227,100072967
    Gene Symbol and Synonyms8430436A10Rik,CYP2U1,P450TEC,SPG49,SPG56
    Uniprot AccessionQ7Z449,Q4V8D1,Q0IIF9
    Uniprot Entry NameCP2U1_HUMAN,CP2U1_RAT,CP2U1_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000155016
    Target ClassificationN/A

    The target: CYP2U1, gene name: CYP2U1, also named as P450TEC, SPG49, SPG56. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.