Anti-DCAF17 monoclonal antibody

Pre-made anti-DCAF17 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DCAF17/DCAF17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0667-Ab-1/ GM-Tg-hg-IP0667-Ab-2Anti-Human DCAF17 monoclonal antibodyHuman
GM-Tg-rg-IP0667-Ab-1/ GM-Tg-rg-IP0667-Ab-2Anti-Rat DCAF17 monoclonal antibodyRat
GM-Tg-mg-IP0667-Ab-1/ GM-Tg-mg-IP0667-Ab-2Anti-Mouse DCAF17 monoclonal antibodyMouse
GM-Tg-cynog-IP0667-Ab-1/ GM-Tg-cynog-IP0667-Ab-2Anti-Cynomolgus/ Rhesus macaque DCAF17 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0667-Ab-1/ GM-Tg-felg-IP0667-Ab-2Anti-Feline DCAF17 monoclonal antibodyFeline
GM-Tg-cang-IP0667-Ab-1/ GM-Tg-cang-IP0667-Ab-2Anti-Canine DCAF17 monoclonal antibodyCanine
GM-Tg-bovg-IP0667-Ab-1/ GM-Tg-bovg-IP0667-Ab-2Anti-Bovine DCAF17 monoclonal antibodyBovine
GM-Tg-equg-IP0667-Ab-1/ GM-Tg-equg-IP0667-Ab-2Anti-Equine DCAF17 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0667-Ab-1/ GM-Tg-hg-IP0667-Ab-2; GM-Tg-rg-IP0667-Ab-1/ GM-Tg-rg-IP0667-Ab-2;
GM-Tg-mg-IP0667-Ab-1/ GM-Tg-mg-IP0667-Ab-2; GM-Tg-cynog-IP0667-Ab-1/ GM-Tg-cynog-IP0667-Ab-2;
GM-Tg-felg-IP0667-Ab-1/ GM-Tg-felg-IP0667-Ab-2; GM-Tg-cang-IP0667-Ab-1/ GM-Tg-cang-IP0667-Ab-2;
GM-Tg-bovg-IP0667-Ab-1/ GM-Tg-bovg-IP0667-Ab-2; GM-Tg-equg-IP0667-Ab-1/ GM-Tg-equg-IP0667-Ab-2
Products NameAnti-DCAF17 monoclonal antibody
Formatmab
Target NameDCAF17
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DCAF17 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0667-Ag-1Recombinant multi-species DCA17/ DCAF17/ C20orf37 protein


    Target information

    Target IDGM-IP0667
    Target NameDCAF17
    Gene ID80067,75763,499807,695470,609326,101089030,614170,100063621
    Gene Symbol and Synonyms2810055O12Rik,4833418A01Rik,A030004A10Rik,A930009G19Rik,C20orf37,C2orf37,DCAF17,RGD1565551
    Uniprot AccessionQ5H9S7,B1H299
    Uniprot Entry NameDCA17_HUMAN,DCA17_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000115827
    Target ClassificationN/A

    The target: DCAF17, gene name: DCAF17, also named as C20orf37, C2orf37. This gene encodes a nuclear transmembrane protein that associates with cullin 4A/damaged DNA binding protein 1 ubiquitin ligase complex. Mutations in this gene are associated with Woodhouse-Sakati syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.