Anti-DENND5B monoclonal antibody

Pre-made anti-DENND5B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DENND5B/DENND5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0682-Ab-1/ GM-Tg-hg-IP0682-Ab-2Anti-Human DENND5B monoclonal antibodyHuman
GM-Tg-rg-IP0682-Ab-1/ GM-Tg-rg-IP0682-Ab-2Anti-Rat DENND5B monoclonal antibodyRat
GM-Tg-mg-IP0682-Ab-1/ GM-Tg-mg-IP0682-Ab-2Anti-Mouse DENND5B monoclonal antibodyMouse
GM-Tg-cynog-IP0682-Ab-1/ GM-Tg-cynog-IP0682-Ab-2Anti-Cynomolgus/ Rhesus macaque DENND5B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0682-Ab-1/ GM-Tg-felg-IP0682-Ab-2Anti-Feline DENND5B monoclonal antibodyFeline
GM-Tg-cang-IP0682-Ab-1/ GM-Tg-cang-IP0682-Ab-2Anti-Canine DENND5B monoclonal antibodyCanine
GM-Tg-bovg-IP0682-Ab-1/ GM-Tg-bovg-IP0682-Ab-2Anti-Bovine DENND5B monoclonal antibodyBovine
GM-Tg-equg-IP0682-Ab-1/ GM-Tg-equg-IP0682-Ab-2Anti-Equine DENND5B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0682-Ab-1/ GM-Tg-hg-IP0682-Ab-2; GM-Tg-rg-IP0682-Ab-1/ GM-Tg-rg-IP0682-Ab-2;
GM-Tg-mg-IP0682-Ab-1/ GM-Tg-mg-IP0682-Ab-2; GM-Tg-cynog-IP0682-Ab-1/ GM-Tg-cynog-IP0682-Ab-2;
GM-Tg-felg-IP0682-Ab-1/ GM-Tg-felg-IP0682-Ab-2; GM-Tg-cang-IP0682-Ab-1/ GM-Tg-cang-IP0682-Ab-2;
GM-Tg-bovg-IP0682-Ab-1/ GM-Tg-bovg-IP0682-Ab-2; GM-Tg-equg-IP0682-Ab-1/ GM-Tg-equg-IP0682-Ab-2
Products NameAnti-DENND5B monoclonal antibody
Formatmab
Target NameDENND5B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DENND5B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0682-Ag-1Recombinant multi-species DEN5B/ DENND5B protein


    Target information

    Target IDGM-IP0682
    Target NameDENND5B
    Gene ID160518,320560,100365679,694421,477651,101089115,516544,100069859
    Gene Symbol and Synonyms9330160C06Rik,D030011O10Rik,DENND5B,Gm17524
    Uniprot AccessionQ6ZUT9
    Uniprot Entry NameDEN5B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170456
    Target ClassificationN/A

    The target: DENND5B, gene name: DENND5B, also named as . Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of triglyceride transport and regulation of catalytic activity. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.