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Anti-DISP1 monoclonal antibody
Pre-made anti-DISP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to DISP1/DISP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0696-Ab-1/ GM-Tg-hg-IP0696-Ab-2 | Anti-Human DISP1 monoclonal antibody | Human |
| GM-Tg-rg-IP0696-Ab-1/ GM-Tg-rg-IP0696-Ab-2 | Anti-Rat DISP1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0696-Ab-1/ GM-Tg-mg-IP0696-Ab-2 | Anti-Mouse DISP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0696-Ab-1/ GM-Tg-cynog-IP0696-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DISP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0696-Ab-1/ GM-Tg-felg-IP0696-Ab-2 | Anti-Feline DISP1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0696-Ab-1/ GM-Tg-cang-IP0696-Ab-2 | Anti-Canine DISP1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0696-Ab-1/ GM-Tg-bovg-IP0696-Ab-2 | Anti-Bovine DISP1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0696-Ab-1/ GM-Tg-equg-IP0696-Ab-2 | Anti-Equine DISP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0696-Ab-1/ GM-Tg-hg-IP0696-Ab-2; GM-Tg-rg-IP0696-Ab-1/ GM-Tg-rg-IP0696-Ab-2; GM-Tg-mg-IP0696-Ab-1/ GM-Tg-mg-IP0696-Ab-2; GM-Tg-cynog-IP0696-Ab-1/ GM-Tg-cynog-IP0696-Ab-2; GM-Tg-felg-IP0696-Ab-1/ GM-Tg-felg-IP0696-Ab-2; GM-Tg-cang-IP0696-Ab-1/ GM-Tg-cang-IP0696-Ab-2; GM-Tg-bovg-IP0696-Ab-1/ GM-Tg-bovg-IP0696-Ab-2; GM-Tg-equg-IP0696-Ab-1/ GM-Tg-equg-IP0696-Ab-2 |
| Products Name | Anti-DISP1 monoclonal antibody |
| Format | mab |
| Target Name | DISP1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-DISP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0696-Ag-1 | Recombinant multi-species DISP1/ DISPA protein |
Target information
| Target ID | GM-IP0696 |
| Target Name | DISP1 |
| Gene ID | 84976,68897,289338,703960,488604,101081946,534637,100049844 |
| Gene Symbol and Synonyms | 1190008H24Rik,DISP1,DISPA |
| Uniprot Accession | Q96F81 |
| Uniprot Entry Name | DISP1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000154309 |
| Target Classification | N/A |
The target: DISP1, gene name: DISP1, also named as DISPA. The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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